Gene
pdgfaa
- ID
- ZDB-GENE-030918-2
- Name
- platelet-derived growth factor alpha polypeptide a
- Symbol
- pdgfaa Nomenclature History
- Previous Names
-
- pdgfa
- Platelet-derived growth factor A (1)
- zgc:100777
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to have platelet-derived growth factor receptor binding activity. Involved in cardiac muscle progenitor cell migration to the midline involved in heart field formation and neural crest cell migration. Predicted to localize to extracellular space. Is expressed in several structures, including anterior neural keel; chordo neural hinge; diencephalon; endoderm; and head. Human ortholog(s) of this gene implicated in malignant glioma. Orthologous to human PDGFA (platelet derived growth factor subunit A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 23 figures from 16 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu754 (15 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cystine-knot cytokine | PDGF/VEGF domain | Platelet-derived growth factor, conserved site | Platelet-derived growth factor, N-terminal |
|---|---|---|---|---|---|
|
UniProtKB:A5PMP7
|
194 | ||||
|
UniProtKB:Q6DC06
|
194 | ||||
|
UniProtKB:Q9DE50
|
195 |
- Genome Browsers
- No data available
| Type | Name | Length (nt) | Analysis |
|---|---|---|---|
| mRNA |
pdgfaa-202
(1)
|
1464 nt |
Interactions and Pathways
No data available
Plasmids
No data available