Gene

ical1

ID

ZDB-GENE-030910-4

Name

islet cell autoantigen 1-like

Symbol

ical1 Nomenclature History

Previous Names

cb781 (1)
ica (1)
wu:fi39e04

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to have protein domain specific binding activity. Predicted to be involved in regulation of transport. Predicted to localize to Golgi apparatus. Is expressed in central nervous system; hatching gland; and polster. Orthologous to human ICA1L (islet cell autoantigen 1 like).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from Thisse et al., 2001

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

cb781 (7 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ical1 Human Ortholog

No data available

Associated With ical1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR006723	Islet cell autoantigen Ica1, C-terminal
Domain	IPR010504	Arfaptin homology (AH) domain
Family	IPR024114	Islet cell autoantigen 1/Ica1-like
Homologous_superfamily	IPR027267	AH/BAR domain superfamily

Domain Details Per Protein

Protein	Length	AH/BAR domain superfamily	Arfaptin homology (AH) domain	Islet cell autoantigen 1/Ica1-like	Islet cell autoantigen Ica1, C-terminal
UniProtKB:A0A8M3BA90 InterPro	514
UniProtKB:F1QC36 InterPro	569
UniProtKB:A0A8M9PLX1 InterPro	497
UniProtKB:A0A8M3B0A0 InterPro	585
UniProtKB:A0A8M3AT71 InterPro	515
UniProtKB:A0A8M2BD37 InterPro	568
UniProtKB:Q803N6 InterPro	569
UniProtKB:A0A8M3AT72 InterPro	586

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
antisense	ottdart00000054282 (1) Ensembl	Havana	575 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	ical1-201 (1) Ensembl	Havana	2486 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	ical1-202 (1) Ensembl	Havana	467 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl
Note: Woods, et al. (2005. Genome Res. 15:1307-1314.) report this gene to be ica based on amino acid similarity to human ICA1. Subsequent analysis suggests it is the ortholog of human ICA1L and mouse Ica1l based on amino acid similarity and conserved synteny.

Citations