Gene

mcm6

ID
ZDB-GENE-030909-6
Name
minichromosome maintenance complex component 6
Symbol
mcm6 Nomenclature History
Previous Names
  • MCM6z (1)
  • cb800 (1)
  • im:7140796
  • wu:fb30d05
  • wu:fc26f09
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to contribute to single-stranded 3'-5' DNA helicase activity. Predicted to be involved in DNA-dependent DNA replication and double-strand break repair via break-induced replication. Predicted to localize to MCM complex and nucleus. Is expressed in central nervous system and proliferative region. Orthologous to human MCM6 (minichromosome maintenance complex component 6).
Genome Resources
Note
None
Expression
All Expression Data
15 figures from 5 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mcm6 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
lactose intolerance Alliance Lactase persistence/nonpersistence 223100
Associated With mcm6 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018525 Mini-chromosome maintenance, conserved site
Domain IPR001208 MCM domain
Domain IPR027925 MCM N-terminal domain
Domain IPR033762 MCM OB domain
Domain IPR041024 Mcm6, C-terminal winged-helix domain
Domain IPR041562 MCM, AAA-lid domain
Family IPR008049 DNA replication licensing factor Mcm6
Family IPR031327 Mini-chromosome maintenance protein
Homologous_superfamily IPR012340 Nucleic acid-binding, OB-fold
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length DNA replication licensing factor Mcm6 Mcm6, C-terminal winged-helix domain MCM, AAA-lid domain MCM domain MCM N-terminal domain MCM OB domain Mini-chromosome maintenance, conserved site Mini-chromosome maintenance protein Nucleic acid-binding, OB-fold P-loop containing nucleoside triphosphate hydrolase
UniProtKB:F1R5P3 830
UniProtKB:A0A0E4AXB8 830
UniProtKB:A3KMS0 830
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations