ZFIN ID: ZDB-GENE-030909-3
Gene Name: glutamate decarboxylase 1b
Gene Symbol: gad1b
Previous Names: gad1, GAD67 (1), gad67 (1)
Location: Chr: 6   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 63 figures from 34 publications
Directly Submitted Expression Data: 4 figures (6 images) from Thisse et al., 2004 [MGC:56253]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Adult (90d-730d, breeding adult)
  basal plate midbrain region, brain, brain glutamatergic neuron, caudal periventricular hypothalamus (all 57) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 2 Genotypes
Knockdown reagents: MO1-gad1b (1)

Allele Type Mutagen Suppliers
sa900 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa2304 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13138 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa15783 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17561 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH gad1b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    spastic quadriplegia Cerebral palsy, spastic quadriplegic, 1 603513
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process gamma-aminobutyric acid biosynthetic process (more)
    Molecular Function carboxy-lyase activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002129 (1)
  • InterPro:IPR015421 (1)
  • InterPro:IPR015422 (1)
  • InterPro:IPR015424 (1)
  • InterPro:IPR021115 (1)
  • PROSITE:PS00392 (1)
  • Pfam:PF00282 (1)
  • EC:4.1.1.15 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA gad1b-001 (1) 3483
    ncRNA gad1b-002 (1) 585
    gad1b-003 (1) 793
    GENE PRODUCT DESCRIPTION
    ANTIBODIES
    Ab1-gad1 (1)
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gad1b
    TgBAC(gad1b:GFP), TgBAC(gad1b:LOXP-RFP-LOXP-GFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    gad1b Contained in: [BAC] DKEY-251E16 (1) (order this)
    gad1b Encodes: [cDNA] MGC:56253 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_194419 (1) 3233 bp
    Genomic GenBank:CR384078 (1) 158424 bp
    Select Tool
    Polypeptide UniProtKB:F1Q5U5 (1) 613 aa
    Sequence Clusters UniGene:81985 (1)
    Sequence Information (all 22)
    OTHER gad1b GENE PAGES
  • Gene:378441 (1)
  • VEGA:OTTDARG00000019714 (1)
  • Ensembl(Zv9):ENSDARG00000027419 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish gad1b 6  
    Human GAD1 2 (2q31)
  • OMIM:605363
  • Gene:2571
  • Mouse Gad1 2 ( 41.63 cM)
  • MGI:95632
  • Gene:14415
  • Orthology Details
    CITATIONS (79)