ZFIN ID: ZDB-GENE-030909-3
Gene Name: glutamate decarboxylase 1b
Gene Symbol: gad1b
Previous Names: gad1, GAD67 (1), gad67 (1)
Location: Chr: 6 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 68 figures from 37 publications
Directly Submitted Expression Data: 4 figures (6 images) from Thisse et al., 2004 [MGC:56253]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Adult (90d-730d, breeding adult)
  basal plate midbrain region, brain, brain glutamatergic neuron, CaP motoneuron (all 62) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
sa900 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa2304 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13138 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa15783 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17561 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-gad1b (1)
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH gad1b HUMAN ORTHOLOG 
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    spastic quadriplegia ?Cerebral palsy, spastic quadriplegic, 1 603513
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process gamma-aminobutyric acid biosynthetic process (more)
    Molecular Function carboxy-lyase activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002129 (1)
  • InterPro:IPR015421 (1)
  • InterPro:IPR015422 (1)
  • InterPro:IPR015424 (1)
  • InterPro:IPR021115 (1)
  • PROSITE:PS00392 (1)
  • Pfam:PF00282 (1)
  • EC:4.1.1.15 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA gad1b-001 (1) 3483
    ncRNA gad1b-002 (1) 585
    gad1b-003 (1) 793
    GENE PRODUCT DESCRIPTION
    ANTIBODIES 
    Ab1-gad1 (1)
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gad1b
    TgBAC(gad1b:GFP), TgBAC(gad1b:LOXP-RFP-LOXP-GFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    gad1bContained in: [BAC] DKEY-251E16 (1) (order this)
    gad1bEncodes: [cDNA] MGC:56253 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_194419 (1) 3233bp
    Genomic GenBank:CR384078 (1) 158424bp
    Select Tool
    Polypeptide UniProtKB:F1Q5U5 (1) 613aa
    Sequence Clusters UniGene:81985 (1)
    Sequence Information (all 22)
    OTHER gad1b GENE PAGES 
  • Gene:378441 (1)
  • VEGA:OTTDARG00000019714 (1)
  • Ensembl(GRCz10):ENSDARG00000027419 (1)
  • ORTHOLOGY for gad1b (Chr: 6) 
    Species Symbol Chromosome Accession # Evidence
    Human GAD1 2
  • Gene:2571
  • OMIM:605363
  • HGNC:4092
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Mouse Gad1 2
  • MGI:95632
  • Gene:14415
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (87)