ZFIN Gene: glud1b

ZFIN ID: ZDB-GENE-030828-1

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Gene Name:	glutamate dehydrogenase 1b
Gene Symbol:	glud1b
Previous Names:	cb719 (1), wu:fb16e02, wu:fb58f12, wu:fe37f03, wu:fj43f02, zgc:192851
Location:	Chr: 12 Mapping Details/Browsers
Nomenclature History

Gene Name:

glutamate dehydrogenase 1b

Gene Symbol:

glud1b

Previous Names:

cb719 (1), wu:fb16e02, wu:fb58f12, wu:fe37f03, wu:fj43f02, zgc:192851

Location:

Chr: 12 Mapping Details/Browsers

Nomenclature History

GENE EXPRESSION
All Expression Data:	18 figures from 3 publications
Directly Submitted Expression Data:	4 figures (6 images) from Thisse et al., 2001 [cb719]
	12 figures (28 images) from Rauch et al., 2003 [fb16e02]
Wild-type Stages, Structures:	Cleavage:2-cell (0.75h-1.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
	adaxial cell , blastomere , brain , endocrine system (all 21)
Curated Microarray Expression:	GEO (1)

GENE EXPRESSION

All Expression Data:

18 figures from 3 publications

Directly Submitted Expression Data:

4 figures (6 images) from Thisse et al., 2001 [cb719]

12 figures (28 images) from Rauch et al., 2003 [fb16e02]

Wild-type Stages, Structures:

Cleavage:2-cell (0.75h-1.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)

adaxial cell, blastomere, brain, endocrine system (all 21) expand

Curated Microarray Expression:

GEO (1)

DISEASE ASSOCIATED WITH glud1b HUMAN ORTHOLOG

Disease Ontology Term	OMIM Term	OMIM Phenotype ID
hyperinsulinemic hypoglycemia	Hyperinsulinism-hyperammonemia syndrome	606762

Ontology	GO Term
Biological Process	cellular amino acid metabolic process (more)
Cellular Component	cellular_component (more)
Molecular Function	oxidoreductase activity (more)

Ontology

GO Term

Biological Process

cellular amino acid metabolic process (more)

Cellular Component

cellular_component (more)

Molecular Function

oxidoreductase activity (more)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR006095 (1) InterPro:IPR006096 (1) InterPro:IPR006097 (1) InterPro:IPR016040 (1) InterPro:IPR033524 (1)	PROSITE:PS00074 (1)	Pfam:PF00208 (1) Pfam:PF02812 (1)

TRANSCRIPTS
Type	Name	Length (bp)	Analysis
mRNA	glud1b-001 (1)	2659	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT Vega

SEGMENT (CLONE AND PROBE) RELATIONSHIPS

glud1bContained in:	[BAC] DKEY-193P11 (1) (order this), DKEY-261G23 (1) (order this)
glud1bContains:	[STS] chunp30314
glud1bEncodes:	[EST] cb719 (1) (order this), fb16e02 (1) (order this), fb58f12 (1), fe37f03 (1), fj43f02 (1) [cDNA] MGC:55630 (1) (order this), MGC:77590 (1) (order this), MGC:192851 (1) (order this)

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_199545 (1)	2659bp	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT Vega
Genomic	GenBank:CR931998 (1)	144369bp	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:Q6P3L9 (1)	542aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast Vega Protein Blast
Sequence Clusters	UniGene:143718 (1)

Type

Accession #

Length (bp/aa)

Analysis

RNA

RefSeq:NM_199545 (1)

2659bp

Select Tool

ZFIN BLAST

NCBI BLAST

Ensembl

UCSC BLAT

Vega

Genomic

GenBank:CR931998 (1)

144369bp

Select Tool

MegaBLAST

Ensembl

Polypeptide

UniProtKB:Q6P3L9 (1)

542aa

Select Tool

ZFIN BLAST

SIB BLAST

Ensembl Protein Blast

Vega Protein Blast

Sequence Clusters

UniGene:143718 (1)

ORTHOLOGY for glud1b (Chr: 12)

Species	Symbol	Chromosome	Accession #	Evidence
Human	GLUD1	10	Gene:2746 OMIM:138130 HGNC:4335	Amino acid sequence comparison (1) Conserved genome location (synteny) (1)

Download Curated Orthology