ZFIN ID: ZDB-GENE-030826-33
Gene Name: major vault protein
Gene Symbol: mvp    Nomenclature History

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Previous Names: cb771 (1), wu:fb52b05, wu:fc02g01

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Involved in brain development; eye development; and neuron projection regeneration. Predicted to localize to cytoplasm and nucleus. Is expressed in several structures, including digestive system; hatching gland; nervous system; periderm; and polster. Human ortholog(s) of this gene implicated in mitral valve prolapse. Orthologous to human MVP (major vault protein).
Genome Resources: Alliance (1),  Gene:373081 (1),  Ensembl(GRCz11):ENSDARG00000021242 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la015084Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44558 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • sq33 Small Deletion Unknown Unknown CRISPR
    sq43 Small Deletion Unknown Unknown CRISPR
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-mvp 1
    CRISPR2-mvp 1
    CRISPR3-mvp
    1
    MO1-mvp N/A 2
    MO2-mvp N/A 2
    MO3-mvp N/A 2
    MO4-mvp N/A 1
    DISEASE ASSOCIATED WITH mvp HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH mvp VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process brain development (more)
    Cellular Component cytoplasm (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA mvp-201 (1)    Ensembl 2975
    mvp-202 (1)    Ensembl 3150
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM mvp No data available
    MARKER RELATIONSHIPS
    mvp Contained in: [BAC] CH211-152F6 (1)
    mvp Encodes: [EST] cb771 (1) (order this), fb52b05 (1), fc02g01 (1)
    [cDNA] MGC:56695 (1), MGC:77610 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_201325 (1) 3007 nt
    Genomic GenBank:BX936308 (1) 110020 nt
    Select Tool
    Polypeptide UniProtKB:E9QEQ6 (1) 870 aa
    Sequence Information (all 22)
    ORTHOLOGY for mvp ( Chr: 3 )
    CITATIONS (39)