ZFIN ID: ZDB-GENE-030826-31
Gene Name: glycogen synthase 2
Gene Symbol: gys2    Nomenclature History

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Previous Names: cb765 (1), zgc:112057

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Predicted to have glycogen (starch) synthase activity. Predicted to be involved in glycogen biosynthetic process and response to glucose. Predicted to localize to cortical actin cytoskeleton; cytosol; and ectoplasm. Is expressed in liver and male organism. Human ortholog(s) of this gene implicated in glycogen storage disease. Orthologous to human GYS2 (glycogen synthase 2).
Genome Resources: Alliance (1),  Gene:373082 (1),  Ensembl(GRCz11):ENSDARG00000004904 (2)
GENE EXPRESSION
All Expression Data: 4 figures from 3 publications
Directly Submitted Expression Data: 2 figures (2 images) from Thisse et al., 2001 [cb765]
Wild-type Stages, Structures: Pharyngula:High-pec (42.0h-48.0h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa20248 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH gys2 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Glycogen storage disease 0, liver 240600
    DISEASE ASSOCIATED WITH gys2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process glycogen biosynthetic process (more)
    Cellular Component cytoplasm (more)
    Molecular Function glycogen (starch) synthase activity (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA gys2-201 (1)    Ensembl 2222
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gys2 No data available
    MARKER RELATIONSHIPS
    gys2 Contained in: [BAC] DKEY-13I19 (1) (order this)
    gys2 Encodes: [EST] cb765 (1) (order this)
    [cDNA] MGC:112057 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001018679 (1) 2602 nt
    Genomic GenBank:BX649476 (1) 126315 nt
    Select Tool
    Polypeptide UniProtKB:A0A2R8Q918 (1) 703 aa
    Sequence Information (all 12)
    ORTHOLOGY for gys2 ( Chr: 4 )
    CITATIONS (32)