Gene
hif1an
- ID
- ZDB-GENE-030826-19
- Name
- hypoxia inducible factor 1 subunit alpha inhibitor
- Symbol
- hif1an Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have several functions, including 2-oxoglutarate-dependent dioxygenase activity; ankyrin repeat binding activity; and protein homodimerization activity. Involved in negative regulation of vasculature development and regulation of vascular endothelial growth factor receptor signaling pathway. Predicted to localize to nucleus and perinuclear region of cytoplasm. Is expressed in several structures, including alar plate midbrain region; central nervous system; immature eye; midbrain hindbrain boundary neural rod; and midbrain neural keel. Orthologous to human HIF1AN (hypoxia inducible factor 1 subunit alpha inhibitor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb728 (10 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cupin-like domain 8 | Hypoxia-inducible factor 1-alpha inhibitor, domain II | JmjC domain | RmlC-like jelly roll fold |
|---|---|---|---|---|---|
|
UniProtKB:P59723
|
344 | ||||
|
UniProtKB:B2GNZ2
|
344 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
hif1an-201
(1)
|
Ensembl | 2,160 nt | ||
| ncRNA |
hif1an-002
(1)
|
Ensembl | 520 nt |
Interactions and Pathways
No data available
Plasmids
No data available