Gene

birc5a

ID
ZDB-GENE-030826-1
Name
baculoviral IAP repeat containing 5a
Symbol
birc5a Nomenclature History
Previous Names
  • survivin 1 (1)
  • survivin (1)
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have cysteine-type endopeptidase inhibitor activity involved in apoptotic process. Involved in several processes, including circulatory system development; positive regulation of angiogenesis; and regulation of apoptotic process. Predicted to localize to cytoplasm; nucleus; and spindle microtubule. Is expressed in axial vasculature; brain; and central nervous system. Human ortholog(s) of this gene implicated in prostate cancer and transitional cell carcinoma. Orthologous to human BIRC5 (baculoviral IAP repeat containing 5).
Genome Resources
Note
None
Expression
All Expression Data
10 figures from 9 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
18 figures from 6 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With birc5a Human Ortholog
No data available
Associated With birc5a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Repeat IPR001370 BIR repeat
Domain Details Per Protein
Protein Length BIR repeat
UniProtKB:F1QTF4 190
UniProtKB:Q90WU9 142
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-birc5 monoclonal IgG2a Mouse
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations