Gene

xiap

ID
ZDB-GENE-030825-7
Name
X-linked inhibitor of apoptosis
Symbol
xiap Nomenclature History
Previous Names
  • XIAP (1)
  • birc4 (1)
  • fb73d01
  • wu:fb73d01 (1)
  • zgc:91873 (1)
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have cysteine-type endopeptidase inhibitor activity involved in apoptotic process and ubiquitin protein ligase activity. Predicted to be involved in mitotic spindle assembly; positive regulation of canonical Wnt signaling pathway; and regulation of cellular protein metabolic process. Predicted to localize to cytoplasm; nucleus; and spindle microtubule. Human ortholog(s) of this gene implicated in X-linked lymphoproliferative syndrome 2 and prostate cancer. Orthologous to human XIAP (X-linked inhibitor of apoptosis).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With xiap Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
X-linked lymphoproliferative syndrome 2 Alliance Lymphoproliferative syndrome, X-linked, 2 300635
Associated With xiap Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001841 Zinc finger, RING-type
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Repeat IPR001370 BIR repeat
Domain Details Per Protein
Protein Length BIR repeat Zinc finger, RING/FYVE/PHD-type Zinc finger, RING-type
UniProtKB:A2RV08 405
UniProtKB:I6L9G1 322
UniProtKB:Q7SXU1 415
UniProtKB:Q8UWH2 405
UniProtKB:F1QMW2 405
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations