ZFIN ID: ZDB-GENE-030820-1
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Gene Name: kinesin family member 1B
Gene Symbol: kif1b
Sequence Ontology ID : SO:0000704

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Previous Names: unm st43, unm_st43, wu:fb74c11

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(Including Attributions)
Location: Chr: 23 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have ATP-dependent microtubule motor activity, plus-end-directed and microtubule binding activity; involved in several processes, including animal organ development, intracellular mRNA  ...
GENE EXPRESSION
All Expression Data: Fig. 1 from Lyons et al., 2009
Wild-type Stages, Structures: Pharyngula:Prim-15 (30.0h-36.0h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la022637Tg Transgenic Insertion Unknown Unknown DNA
sa8450 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa16498 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa24361 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa37744 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa44007 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa44008 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa44009 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • st43 Point Mutation Unknown Unknown
  • Zebrafish International Resource Center (ZIRC) (order this)
    • Targeting reagents:
    PHENOTYPE
    Data: 10 figures from 3 publications
    Observed in:
    DISEASE ASSOCIATED WITH kif1b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Charcot-Marie-Tooth disease type 2A1 ?Charcot-Marie-Tooth disease, type 2A1 118210
    pheochromocytoma Pheochromocytoma 171300
    {Neuroblastoma, susceptibility to, 1} 256700
    DISEASE ASSOCIATED WITH kif1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process neuron projection maintenance (more)
    Cellular Component kinesin complex (more)
    Molecular Function ATP binding (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000253 (1)
  • InterPro:IPR001752 (1)
  • InterPro:IPR001849 (1)
  • InterPro:IPR008984 (1)
  • InterPro:IPR011993 (1)
  • InterPro:IPR019821 (1)
  • InterPro:IPR022140 (1)
  • InterPro:IPR022164 (1)
  • InterPro:IPR027417 (1)
  • InterPro:IPR027640 (1)
  • InterPro:IPR032405 (1)
  • InterPro:IPR036961 (1)
    		•
  • PROSITE:PS00411 (1)
  • PROSITE:PS50003 (1)
  • PROSITE:PS50067 (1)
    		•
  • Pfam:PF00169 (1)
  • Pfam:PF00225 (1)
  • Pfam:PF00498 (1)
  • Pfam:PF12423 (1)
  • Pfam:PF12473 (1)
  • Pfam:PF16183 (1)
    		•
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA kif1b-203 (1) 8161
    Select Tool
    kif1b-204 (1) 4012
    Select Tool
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM kif1b No data available
    MARKER RELATIONSHIPS
    kif1bContained in: [BAC] CH211-129O18 (1) (order this), DKEY-259L18 (1) (order this)
    kif1bEncodes: [EST] 095-d12-2 (1), fb74c11
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_194382 (1) 5477bp
    Select Tool
    Genomic GenBank:BX571850 (1) 236136bp Blast at MegaBLAST
    Polypeptide UniProtKB:C0LSN9 (1) 1770aa
    Select Tool
    Sequence Clusters UniGene:159713 (1)
    Sequence Information (all 65)
    OTHER kif1b GENE PAGES
  • Alliance (1)
  • Gene:369190 (1)
  • VEGA:OTTDARG00000021340 (1)
  • Ensembl(GRCz11):ENSDARG00000037020 (2)
    • ORTHOLOGY for kif1b (Chr: 23)
    CITATIONS (32)