ZFIN ID: ZDB-GENE-030805-2
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.
Gene Name: platelet-derived growth factor receptor, beta polypeptide
Gene Symbol: pdgfrb
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: pdgfrb2

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Unmapped
Nomenclature History
GENE EXPRESSION
All Expression Data: 13 figures from 8 publications
Wild-type Stages, Structures: Segmentation:5-9 somites (11.66h-14.0h) to Larval:Day 4 (96.0h-120.0h)
  anatomical structure, brain vasculature pericyte, central artery, cranial blood vessel (all 19) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la027549Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa16389 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa22413 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • um148 Small Deletion Unknown Frameshift, Premature Stop TALEN
    Targeting reagents: MO1-pdgfrb (1), TALEN1-pdgfrb (1)
    PHENOTYPE
    Data: 2 figures from 2 publications
    Observed in: anatomical structure, intersegmental vessel
    DISEASE ASSOCIATED WITH pdgfrb HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    basal ganglia calcification Basal ganglia calcification, idiopathic, 4 615007
    infantile myofibromatosis Myofibromatosis, infantile, 1 228550
    Myeloproliferative disorder with eosinophilia 131440
    Kosaki overgrowth syndrome 616592
    Premature aging syndrome, Penttinen type 601812
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cerebellum vasculature development (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000719 (1)
  • InterPro:IPR001245 (1)
  • InterPro:IPR001824 (1)
  • InterPro:IPR003598 (1)
  • InterPro:IPR003599 (1)
  • InterPro:IPR007110 (1)
  • InterPro:IPR008266 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR013098 (1)
  • InterPro:IPR013783 (1)
  • InterPro:IPR017441 (1)
  • InterPro:IPR020635 (1)
    		•
  • PROSITE:PS00107 (1)
  • PROSITE:PS00109 (1)
  • PROSITE:PS00240 (1)
  • PROSITE:PS50011 (1)
  • PROSITE:PS50835 (1)
    		•
  • Pfam:PF07679 (1)
  • Pfam:PF07714 (1)
    		•
    TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES
    Ab1-pdgfrb (1)
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM pdgfrb
    TgBAC(pdgfrb:Citrine), tgbac(pdgfrb:egfp), tgbac(pdgfrb:gal4ff), tgbac(pdgfrb:mcherry)
    MARKER RELATIONSHIPSNo data available
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001190933 (1) 3195bp
    Select Tool
    Genomic GenBank:CABZ01112581 (1) 22588bp
    Select Tool
    Polypeptide UniProtKB:D9MNA7 (1) 1064aa
    Select Tool
    Sequence Clusters UniGene:159213 (1)
    Sequence Information (all 20)
    OTHER pdgfrb GENE PAGES
  • Gene:559529 (1)
    • ORTHOLOGY for pdgfrb ( Unmapped )
    CITATIONS (30)