Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030805-2
Gene Name: platelet-derived growth factor receptor, beta polypeptide
Gene Symbol: pdgfrb
Previous Name: pdgfrb2
Location: Chr: 14   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 8 figures from 3 publications
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
  central artery, dorsal aorta, dorsal longitudinal anastomotic vessel, floor plate neural tube (all 8) expand
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: la027549Tg, sa16389, sa22413
Knockdown reagents: MO1-pdgfrb (1)
PHENOTYPE
Data: Fig. 5 from Wiens et al., 2010
Observed in: intersegmental vessel

Phenotype of Human Orthologue OMIM Phenotype ID
Basal ganglia calcification, idiopathic, 4 615007
Myeloproliferative disorder with eosinophilia 131440
Myofibromatosis, infantile, 1 228550
GENE ONTOLOGY
Ontology GO Term
Biological Process angiogenesis (more)
Cellular Component integral component of membrane (more)
Molecular Function ATP binding (more)
GO Terms (all 17)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000719 (1)
  • InterPro:IPR001245 (1)
  • InterPro:IPR001824 (1)
  • InterPro:IPR003599 (1)
  • InterPro:IPR007110 (1)
  • InterPro:IPR008266 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR013098 (1)
  • InterPro:IPR013783 (1)
  • InterPro:IPR016243 (1)
  • InterPro:IPR017441 (1)
  • InterPro:IPR020635 (1)
  • InterPro:IPR027288 (1)
  • PROSITE:PS00107 (1)
  • PROSITE:PS00109 (1)
  • PROSITE:PS00240 (1)
  • PROSITE:PS50011 (1)
  • PROSITE:PS50835 (1)
  • Pfam:PF07679 (1)
  • Pfam:PF07714 (1)
  • EC:2.7.10.1 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pdgfrb No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS No data available
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001190933 (1) 3195 bp
    Genomic GenBank:CABZ01112581 (1) 22588 bp
    Polypeptide UniProtKB:D9MNA7 (1) 1064 aa
    Sequence Clusters UniGene:159213 (1)
    Sequence Information (all 13)
    OTHER pdgfrb GENE PAGES
  • Gene:559529 (1)
  • Ensembl(Zv9):ENSDARG00000057345 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish pdgfrb 14  
    Human PDGFRB 5 (5q33.1)
  • OMIM:173410
  • Gene:5159
  • Mouse Pdgfrb 18 ( 34.41 cM)
  • MGI:97531
  • Gene:18596
  • Orthology Details
    CITATIONS (19)