ZFIN ID: ZDB-GENE-030805-2
Gene Name: platelet-derived growth factor receptor, beta polypeptide
Gene Symbol: pdgfrb
Previous Name: pdgfrb2
Location: Unmapped
Nomenclature History
GENE EXPRESSION
All Expression Data: 9 figures from 4 publications
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
  central artery, cranial blood vessel, dorsal aorta, dorsal longitudinal anastomotic vessel (all 11) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
la027549Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16389 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa22413 Point Mutation ENU
    Targeting reagents: MO1-pdgfrb (1), TALEN1-pdgfrb (1)
    PHENOTYPE
    Data: Fig. 5 from Wiens et al., 2010
    Observed in: intersegmental vessel
    DISEASE ASSOCIATED WITH pdgfrb HUMAN ORTHOLOG 
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    basal ganglia calcification Basal ganglia calcification, idiopathic, 4 615007
    infantile myofibromatosis Myofibromatosis, infantile, 1 228550
    Kosaki overgrowth syndrome 616592
    Myeloproliferative disorder with eosinophilia 131440
    Premature aging syndrome, Penttinen type 601812
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process cerebellum vasculature development (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000719 (1)
  • InterPro:IPR001245 (1)
  • InterPro:IPR001824 (1)
  • InterPro:IPR003599 (1)
  • InterPro:IPR007110 (1)
  • InterPro:IPR008266 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR013098 (1)
  • InterPro:IPR013783 (1)
  • InterPro:IPR016243 (1)
  • InterPro:IPR017441 (1)
  • InterPro:IPR020635 (1)
  • InterPro:IPR027288 (1)
  • PROSITE:PS00107 (1)
  • PROSITE:PS00109 (1)
  • PROSITE:PS00240 (1)
  • PROSITE:PS50011 (1)
  • PROSITE:PS50835 (1)
  • Pfam:PF07679 (1)
  • Pfam:PF07714 (1)
  • EC:2.7.10.1 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pdgfrb
    TgBAC(pdgfrb:Citrine)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS No data available
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001190933 (1) 3195bp
    Genomic GenBank:CABZ01112581 (1) 22588bp
    Polypeptide UniProtKB:D9MNA7 (1) 1064aa
    Sequence Clusters UniGene:159213 (1)
    Sequence Information (all 12)
    OTHER pdgfrb GENE PAGES 
  • Gene:559529 (1)
  • ORTHOLOGY for pdgfrb ( Unmapped ) 
    Species Symbol Chromosome Accession # Evidence
    Human PDGFRB 5
  • Gene:5159
  • OMIM:173410
  • HGNC:8804
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Mouse Pdgfrb 18
  • MGI:97531
  • Gene:18596
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (22)