ZFIN ID: ZDB-GENE-030724-4
Gene Name: gonadotropin-releasing hormone 3
Gene Symbol: gnrh3    Nomenclature History

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Previous Name: sGnRH (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have gonadotropin hormone-releasing hormone activity and gonadotropin-releasing hormone receptor binding activity. Involved in brain development and camera-type eye development. Predicted to localize to the extracellular space. Is expressed in several structures, including heart; liver; nervous system; pleuroperitoneal region; and skeletal muscle cell.
Genome Resources: Alliance (1),  Gene:360141 (1),  Ensembl(GRCz11):ENSDARG00000056214 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
zf713 Complex Unknown Unknown TALEN
zf1051 Indel Exon 2 Unknown TALEN
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-gnrh3 N/A 1
MO2-gnrh3 N/A 1
MO3-gnrh3 N/A 1
MO4-gnrh3 N/A 1
MO5-gnrh3 N/A 1
MO6-gnrh3 N/A 1
MO7-gnrh3 N/A 1
TALEN1-gnrh3 1
TALEN2-gnrh3 1
PHENOTYPE
Data: 3 figures from 2 publications
Observed in:
DISEASE ASSOCIATED WITH gnrh3 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH gnrh3 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process brain development (more)
Cellular Component extracellular region (more)
Molecular Function hormone activity (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Conserved_site IPR002012 Gonadotropin-releasing hormone
Family IPR019792 Gonadoliberin
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA gnrh3-201 (1)    Ensembl 444
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES
Name Type Isotype Host Organism Assay Source Publications
Ab1-gnrh3 monoclonal Mouse IHC 5
Ab2-gnrh3 polyclonal Rabbit IHC 1
Ab3-gnrh3 polyclonal Rabbit IHC 1
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM gnrh3
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg(-6gnrh3:emGFP) gnrh3 emGFP Danio rerio 1 8
Tg(gnrh3:EGFP) gnrh3 EGFP Danio rerio 1 16
Tg(gnrh3:GAL4FF) gnrh3 GAL4FF Danio rerio 1 1
Tg(gnrh3:GFP) gnrh3 GFP Danio rerio 1 5
Tg(gnrh3:GFP-Eco.Lacz) gnrh3 GFP Danio rerioEscherichia coli 1 3
Tg(gnrh3:Tomato) gnrh3 Tomato Danio rerio 1 4
MARKER RELATIONSHIPS
gnrh3 Contained in: [BAC] CH211-207N2 (1)
gnrh3 Encodes: [cDNA] MGC:194946 (1), MGC:194958 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_182887 (1) 433 bp
Genomic GenBank:BX005375 (1) 214178 bp Blast at MegaBLAST
Polypeptide UniProtKB:F1QW13 (1) 94 aa
Sequence Clusters UniGene:82596 (1)
Sequence Information (all 20)
ORTHOLOGY for gnrh3 ( Chr: 17 )
CITATIONS (124)