ZFIN ID: ZDB-GENE-030723-3
Gene Name: transforming growth factor, beta 2
Gene Symbol: tgfb2
Sequence Ontology ID : SO:0000704

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Previous Name: tgf beta 2 (1)

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(Including Attributions)
Location: Chr: 16 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have cytokine activity and type II transforming growth factor beta receptor binding activity; involved in hard palate development and sclerotome development; predicted to localize to the  ...
GENE EXPRESSION
All Expression Data: 14 figures from 7 publications
Directly Submitted Expression Data: 5 figures (8 images) from Chen et al., 2003 [tgf_beta_2]
Wild-type Stages, Structures: Gastrula:Bud (10.0h-10.33h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents:
PHENOTYPE
Data: 2 figures from 2 publications
Observed in:
DISEASE ASSOCIATED WITH tgfb2 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Loeys-Dietz syndrome Loeys-Dietz syndrome 4 614816
Loeys-Dietz syndrome 4 Loeys-Dietz syndrome 4 614816
DISEASE ASSOCIATED WITH tgfb2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process hard palate development (more)
Cellular Component extracellular region (more)
Molecular Function growth factor activity (more)
GO Terms (all 17)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001111 (1)
  • InterPro:IPR001839 (1)
  • InterPro:IPR003940 (1)
  • InterPro:IPR015615 (1)
  • InterPro:IPR016319 (1)
  • InterPro:IPR017948 (1)
  • InterPro:IPR029034 (1)
  • PROSITE:PS00250 (1)
  • PROSITE:PS51362 (1)
  • Pfam:PF00019 (1)
  • Pfam:PF00688 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tgfb2-001 (1) 1242
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tgfb2 No data available
    MARKER RELATIONSHIPS
    tgfb2Contained in: [BAC] CH211-65B3 (1) (order this), DKEY-288I20 (1) (order this)
    tgfb2Encodes: [EST] tgf_beta_2 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_194385 (1) 1242bp
    Genomic GenBank:CU207260 (1) 172886bp
    Select Tool
    Polypeptide UniProtKB:F8W4A6 (1) 413aa
    Sequence Clusters UniGene:89477 (1)
    Sequence Information (all 11)
    OTHER tgfb2 GENE PAGES
  • Alliance (1)
  • Gene:369194 (1)
  • VEGA:OTTDARG00000033939 (1)
  • Ensembl(GRCz11):ENSDARG00000027087 (2)
  • ORTHOLOGY for tgfb2 (Chr: 16)
    CITATIONS (38)