ZFIN ID: ZDB-GENE-030722-10
Gene Name: bromodomain containing 8
Gene Symbol: brd8    Nomenclature History

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Previous Names: cb555 (1), wu:fj66h01, wu:fj84g12, zgc:66249

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Involved in hematopoietic progenitor cell differentiation. Predicted to localize to NuA4 histone acetyltransferase complex. Is expressed in nervous system; pectoral fin musculature; pharyngeal arch 3-7 skeleton; post-vent region; and primordial germ cell. Orthologous to human BRD8 (bromodomain containing 8).
Genome Resources: Alliance (1),  Gene:337414 (1),  Ensembl(GRCz11):ENSDARG00000025071 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa265 Point Mutation Unknown Premature Stop ENU
sa15090 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31973 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-brd8
    1
    CRISPR2-brd8
    1
    MO1-brd8 N/A 1
    MO2-brd8 N/A 1
    MO3-brd8 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH brd8 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH brd8 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process hematopoietic progenitor cell differentiation (more)
    Cellular Component NuA4 histone acetyltransferase complex (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA brd8-001 (1) 3244
    brd8-202 (1)    Ensembl 2446
    brd8-203 (1)    Ensembl 903
    brd8-204 (1)    Ensembl 801
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM brd8 No data available
    MARKER RELATIONSHIPS
    brd8 Contained in: [BAC] CH73-82K19 (1), CH73-168C14 (1), CH211-39I2
    brd8 Encodes: [EST] cb555 (1) (order this), fj66h01 (1), fj84g12 (1)
    [cDNA] MGC:66249 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_212777 (1) 3218 nt
    Genomic GenBank:BX901966 (1) 145325 nt
    Select Tool
    Polypeptide UniProtKB:Q803V1 (1) 863 aa
    Sequence Information (all 36)
    ORTHOLOGY for brd8 ( Chr: 14 )
    CITATIONS (24)