Gene

fgf10a

ID
ZDB-GENE-030715-1
Name
fibroblast growth factor 10a
Symbol
fgf10a Nomenclature History
Previous Names
  • fgf10
  • dae
  • daedalus
  • wu:fd11d03 (1)
  • zgc:109774
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have chemoattractant activity; growth factor activity; and type 2 fibroblast growth factor receptor binding activity. Involved in several processes, including embryonic pectoral fin morphogenesis; posterior lateral line development; and regulation of hematopoietic stem cell differentiation. Predicted to localize to cytoplasm and extracellular space. Is expressed in several structures, including ectoderm; fin bud; gut; head; and lateral line system. Human ortholog(s) of this gene implicated in LADD syndrome and aplasia of lacrimal and salivary glands. Orthologous to human FGF10 (fibroblast growth factor 10).
Genome Resources
Note
None
Expression
All Expression Data
90 figures from 52 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
17 figures from 11 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fgf10a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
aplasia of lacrimal and salivary glands Alliance Aplasia of lacrimal and salivary glands 180920
LADD syndrome Alliance LADD syndrome 149730
Associated With fgf10a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR002209 Fibroblast growth factor family
Family IPR028252 Fibroblast growth factor 10
Homologous_superfamily IPR008996 Cytokine IL1/FGF
Domain Details Per Protein
Protein Length Cytokine IL1/FGF Fibroblast growth factor 10 Fibroblast growth factor family
UniProtKB:Q800L8 191
UniProtKB:Q4VBV7 201
UniProtKB:Q8AY90 201
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations