ZFIN Gene: fgf10a

ZFIN ID: ZDB-GENE-030715-1

ZFIN ID: ZDB-GENE-030715-1

Gene Name:

fibroblast growth factor 10a

Gene Symbol:

fgf10a

Sequence Ontology ID :

SO:0000704

Previous Names:

fgf10, dae, daedalus, wu:fd11d03 (1), zgc:109774

Location:

Chr: 21 Mapping Details/Browsers

Nomenclature History

AUTOMATED DESCRIPTION

Predicted to have fibroblast growth factor receptor binding activity and growth factor activity. Involved in several processes, including embryonic pectoral fin morphogenesis; hard palate ...

GENE EXPRESSION
All Expression Data:	84 figures from 48 publications
Directly Submitted Expression Data:	6 figures (13 images) from Thisse et al., 2004 [MGC:109774]
	7 figures (19 images) from Thisse et al., 2005 [eu110]
Wild-type Stages, Structures:	Gastrula:50%-epiboly (5.25h-5.66h) to Larval:Days 21-29 (21d-30d, 7.8mm, 10 teeth)
	anterior lateral line anterior lateral line neuromast anterior lateral line placode anterior macula esophagus fin bud gut intestinal bulb lateral line lateral line ganglion lateral line primordium lateral line system mandibular arch skeleton cranial neural crest cell maxilla cranial neural crest cell mesenchymal cell mesenchyme mesenchyme pectoral fin mesoderm pectoral fin bud neuromast neuromast hair cell olfactory placode olfactory region cranial neural crest cell oral ectoderm oral region ectoderm otic placode anterior region otic placode otic vesicle anterior crista otic vesicle anterior region otic vesicle lateral crista otic vesicle posterior crista otic vesicle paired fin pancreatic system mesenchyme pectoral fin pectoral fin bud mesenchyme pectoral fin bud pectoral fin field lateral plate mesoderm pectoral fin field pelvic fin bud mesenchyme periderm pharyngeal arch pharyngeal arch 3-7 posterior lateral line neuromast posterior lateral line placode posterior lateral line primordium posterior lateral plate mesoderm protoneuromast central region swim bladder mesenchyme swim bladder swim bladder bud mesenchyme tail bud trunk unspecified whole organism
Curated Microarray Expression:	GEO (1)

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
sa23903	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
t24030	Point Mutation	Unknown	Missense	ENU	European Zebrafish Resource Center (EZRC) (order this)
tbvbo	Point Mutation	Unknown	Premature Stop	ENU

Targeting reagents:

PHENOTYPE

Data:

17 figures from 11 publications

Observed in:

DISEASE ASSOCIATED WITH fgf10a HUMAN ORTHOLOG

Disease Ontology Term	OMIM Term	OMIM Phenotype ID
LADD syndrome	LADD syndrome	149730
	Aplasia of lacrimal and salivary glands	180920

DISEASE ASSOCIATED WITH fgf10a VIA EXPERIMENTAL MODELS No data available

GENE ONTOLOGY

Ontology	GO Term
Biological Process	liver development (more)
Cellular Component	extracellular region (more)
Molecular Function	fibroblast growth factor receptor binding (more)

GO Terms (all 11)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR002209 (1) InterPro:IPR008996 (1) InterPro:IPR028252 (1)	Pfam:PF00167 (1)

TRANSCRIPTS
Type	Name	Length (bp)	Analysis
mRNA	fgf10a-201 (1)	2005	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

GENE PRODUCT DESCRIPTION

INTERACTIONS AND PATHWAYS

ANTIBODIESNo data available

PLASMIDSNo data available

CONSTRUCTS WITH SEQUENCES FROM fgf10a

MARKER RELATIONSHIPS

fgf10aContained in:	[BAC] CH211-262I10 (1) (order this)
fgf10aEncodes:	[EST] eu110 (1), fd11d03 (1) [cDNA] MGC:109774 (order this), MGC:192178 (1) (order this)

SEQUENCE INFORMATION

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_182870 (1)	2017bp	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX927394 (1)	164899bp	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:Q4VBV7 (1)	201aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast
Sequence Clusters	UniGene:79709 (1)

Sequence Information (all 20)

OTHER fgf10a GENE PAGES

Alliance (1)

Gene:359830 (1)

VEGA:OTTDARG00000031555 (1)

Ensembl(GRCz11):ENSDARG00000030932 (1)

ORTHOLOGY for fgf10a (Chr: 21)

CITATIONS (120)

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