ZFIN ID: ZDB-GENE-030616-82
Gene Name: ciliary neurotrophic factor receptor
Gene Symbol: cntfr    Nomenclature History

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Previous Names: cb549 (1), fj33e02, sb:cb549, si:bz76a6.1, si:dz248f2.1, si:rp71-76a6.1, wu:fj33e02

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have cytokine binding activity and cytokine receptor activity. Involved in positive regulation of axon regeneration. Predicted to localize to external side of plasma membrane and receptor complex. Is expressed in several structures, including central nervous system; cranial ganglion; hindbrain neural plate; immature eye; and pectoral fin musculature. Orthologous to human CNTFR (ciliary neurotrophic factor receptor).
Genome Resources: Alliance (1),  Gene:368438 (1),  Ensembl(GRCz11):ENSDARG00000028661 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la027138Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cntfr HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cntfr VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of axon regeneration (more)
    Cellular Component membrane (more)
    Molecular Function cytokine receptor activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cntfr-201 (1)    Ensembl 2442
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cntfr No data available
    MARKER RELATIONSHIPS
    cntfr Contained in: [BAC] CH73-176H21 (1), CH211-13K18 (1), DKEY-256K14 (1) (order this), RP71-76A6 (1)
    [PAC] BUSM1-248F2
    cntfr Encodes: [EST] cb549 (order this), fj33e02, fc09d01 (1)
    [cDNA] cssl:d233 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001098242 (1) 2468 nt
    Genomic RefSeq:NW_018394774 (1) Blast at MegaBLAST
    Polypeptide UniProtKB:A4JYQ0 (1) 357 aa
    Sequence Information (all 29)
    ORTHOLOGY for cntfr ( Chr: 10 )
    CITATIONS (33)