ZFIN ID: ZDB-GENE-030616-74
Gene Name: arrestin 3b, retinal (X-arrestin)
Gene Symbol: arr3b    Nomenclature History

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Previous Names: arr3 (1), si:bz46j2.6, zgc:73331

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Predicted to have G protein-coupled receptor binding activity. Predicted to be involved in G protein-coupled receptor internalization and visual perception. Is expressed in neural plate; optic primordium; optic vesicle; photoreceptor cell; and visual system. Human ortholog(s) of this gene implicated in myopia. Orthologous to human ARR3 (arrestin 3).
Genome Resources: Alliance (1),  Gene:796867 (1),  Ensembl(GRCz11):ENSDARG00000098475 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-arr3b N/A 2
MO2-arr3b N/A 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH arr3b HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Myopia 26, X-linked, female-limited 301010
DISEASE ASSOCIATED WITH arr3b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process response to stimulus (more)
Molecular Function G protein-coupled receptor binding (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA arr3b-201 (1)    Ensembl 1755
arr3b-203 (1)    Ensembl 728
ncRNA arr3b-003 (1)    Ensembl 1029
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES
Name Type Isotype Host Organism Assay Source Publications
Ab1-arr3b Chicken IHC 2
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM arr3b No data available
MARKER RELATIONSHIPS
arr3b Contained in: [BAC] CH211-285J6 (1), RP71-46J2 (1)
arr3b Encodes: [cDNA] MGC:73331 (1), MGC:173982 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_200792 (1) 1721 nt
Genomic GenBank:BX088596 142350 nt
Select Tool
Polypeptide UniProtKB:A0A0R4IMS8 (1) 364 aa
Sequence Information (all 20)
ORTHOLOGY for arr3b ( Chr: 14 )
CITATIONS (32)