ZFIN ID: ZDB-GENE-030616-61
Gene Name: OTU deubiquitinase 5a
Gene Symbol: otud5a    Nomenclature History

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Previous Names: otud5, si:bz30i22.1, si:rp71-30i22.1 (1), zgc:154072

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have Lys63-specific deubiquitinase activity and thiol-dependent ubiquitin-specific protease activity. Predicted to be involved in protein K48-linked deubiquitination; protein K63-linked deubiquitination; and response to lipopolysaccharide. Orthologous to human OTUD5 (OTU deubiquitinase 5).
Genome Resources: Alliance (1),  Gene:555459 (1),  Ensembl(GRCz11):ENSDARG00000059006 (2)
Note: novel protein similar to human FLJ12550
GENE EXPRESSION
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la026702Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21204 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34303 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34304 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41124 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45310 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-otud5a N/A 1
    DISEASE ASSOCIATED WITH otud5a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH otud5a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein K48-linked deubiquitination (more)
    Cellular Component cellular_component (more)
    Molecular Function thiol-dependent ubiquitin-specific protease activity (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA otud5a-201 (1)    Ensembl 914
    otud5a-202 (1)    Ensembl 2312
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM otud5a No data available
    MARKER RELATIONSHIPS
    otud5a Contained in: [BAC] DKEY-83K24 (1) (order this), RP71-30I22 (1)
    otud5a Encodes: [cDNA] MGC:154072 (1), MGC:174976 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001075110 (1) 2308 nt
    Genomic GenBank:CR450685 (1) 195473 nt
    Select Tool
    Polypeptide UniProtKB:Q08BW0 (1) 560 aa
    Sequence Information (all 18)
    ORTHOLOGY for otud5a ( Chr: 8 )
    CITATIONS (28)