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ZIRC
ZFIN ID: ZDB-GENE-030616-396
Gene Name: si:busm1-228j01.6
Gene Symbol: si:busm1-228j01.6    Nomenclature History

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Previous Names: si:dz228j01.6, zgc:123114 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to be involved in antigen processing and presentation and immune response. Predicted to localize to the MHC class II protein complex and integral component of membrane. Human ortholog(s) of this gene implicated in several diseases, including autoimmune hypersensitivity disease (multiple); bacterial infectious disease (multiple); bone inflammation disease (multiple); cellulitis (multiple); and eye disease (multiple). Orthologous to several human genes including HLA-DPB1 (major histocompatibility complex, class II, DP beta 1).
Genome Resources: Alliance (1),  Gene:368846 (1),  Ensembl(GRCz11):ENSDARG00000041705 (1)
Note: novel protein similar to parts of MHC class II beta chain and MHC class II antigen

Nomenclature Note: This gene is derived from the zebrafish genome sequencing and annotation project. When more is known about the gene, the current nomenclature will be replaced with more traditional zebrafish gene nomenclature. The prefix 'si:' indicates that this gene is represented by annotated genomic sequence from the Sanger Institute.

GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa34469 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH si:busm1-228j01.6 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH si:busm1-228j01.6 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process antigen processing and presentation (more)
    Cellular Component integral component of membrane (more)
    GO Terms (all 5)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA si:busm1-228j01.6-001 (1) 912
    si:busm1-228j01.6-201 (1)    Ensembl 1136
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM si:busm1-228j01.6 No data available
    MARKER RELATIONSHIPS
    si:busm1-228j01.6 Contained in: [BAC] CH73-308B14 (1) (order this)
    [PAC] BUSM1-228J01 (1) (order this)
    si:busm1-228j01.6 Encodes: [cDNA] MGC:123114 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001077753 (1) 1167 bp
    Genomic GenBank:CU914776 (1) 112746 bp
    Select Tool
    Polypeptide UniProtKB:Q95HJ4 (1) 303 aa
    Sequence Clusters UniGene:92213 (1)
    Sequence Information (all 15)
    ORTHOLOGY for si:busm1-228j01.6 ( Chr: 8 )
    CITATIONS (15)