ZFIN ID: ZDB-GENE-030616-162
Gene Name: myosin, heavy chain 10, non-muscle
Gene Symbol: myh10    Nomenclature History

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Previous Names: nm-mhc-b (1), si:dz150i12.3, wu:fc46h07, wu:fy19d11

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have ATP binding activity; actin filament binding activity; and motor activity. Involved in actin filament bundle distribution; midbrain-hindbrain boundary morphogenesis; and regulation of cell shape. Predicted to localize to myosin complex. Is expressed in several structures, including nervous system; neural tube; paraxial mesoderm; swim bladder bud; and tail bud. Orthologous to human MYH10 (myosin heavy chain 10).
Genome Resources: Alliance (1),  Gene:555454 (1),  Ensembl(GRCz11):ENSDARG00000000103 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa2305 Point Mutation Unknown Splice Site ENU
sa5750 Point Mutation Unknown Splice Site ENU
sa20627 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33803 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40631 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-myh10 N/A 1
    DISEASE ASSOCIATED WITH myh10 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH myh10 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process actin filament bundle distribution (more)
    Cellular Component myosin complex (more)
    Molecular Function actin binding (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA myh10-201 (1)    Ensembl 7428
    myh10-202 (1)    Ensembl 7446
    ottdart00000001857 (1) 507
    ncRNA myh10-003 (1)    Ensembl 509
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-myh10 monoclonal Mouse IHC Abcam plc
    2
    Ab3-myh10 polyclonal Rabbit IHC, WB 1
    PLASMIDS
    Addgene:nm-mhc-b
    CONSTRUCTS WITH SEQUENCES FROM myh10 No data available
    MARKER RELATIONSHIPS
    myh10 Contained in: [BAC] CH73-354J22 (1), CH211-146L13 (1)
    [PAC] BUSM1-150I12 (1), BUSM1-204D19
    myh10 Encodes: [EST] eu795 (1), faa51a11, fc46h07 (1), fy19d11 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_005165720 (1) 7449 nt
    Genomic GenBank:AL954384 (1) 162560 nt
    Select Tool
    Polypeptide UniProtKB:F1R3G4 (1) 1992 aa
    Sequence Information (all 41)
    ORTHOLOGY for myh10 ( Chr: 6 )
    CITATIONS (33)