ZFIN ID: ZDB-GENE-030603-1
Gene Name: MAX dimerization protein MGA a
Gene Symbol: mgaa    Nomenclature History

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Previous Names: mga, im:7137698, sb:eu601, wu:fd99g02

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Exhibits molecular function regulator. Contributes to transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including animal organ development; determination of ventral identity; and pathway-restricted SMAD protein phosphorylation. Localizes to SMAD protein complex. Is expressed in several structures, including gut; head; pectoral fin bud; and yolk syncytial layer. Orthologous to human MGA (MAX dimerization protein MGA).
Genome Resources: Alliance (1),  Gene:569620 (1),  Ensembl(GRCz11):ENSDARG00000078784 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb801 Small Deletion Exon 2 Frameshift, Premature Stop TALEN
sa865 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa9048 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18203 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36332 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36333 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39148 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-mgaa N/A 1
    MO2-mgaa N/A 1
    MO3-mgaa N/A 1
    MO4-mgaa N/A 1
    MO5-mgaa N/A 1
    MO6-mgaa N/A 1
    TALEN1-mgaa 1
    DISEASE ASSOCIATED WITH mgaa HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH mgaa VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process determination of ventral identity (more)
    Cellular Component SMAD protein complex (more)
    Molecular Function CONTRIBUTES_TO   transcription regulatory region sequence-specific DNA binding (more)
    GO Terms (all 24)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA mgaa-202 (1)    Ensembl 538
    mgaa-203 (1)    Ensembl 11931
    mgaa-204 (1)    Ensembl 251
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab3-mgaa 1
    Ab1-mgaa IHC 1
    Ab2-mgaa IHC 1
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM mgaa No data available
    MARKER RELATIONSHIPS
    mgaa Contained in: [BAC] DKEY-89F23 (1) (order this)
    mgaa Contains: [SNP] rs3728833 (1)
    mgaa Encodes: [EST] eu601 (1), fd99g02, IMAGE:7137698 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001170739 (1) 8208 nt
    Genomic GenBank:CR352284 (1) 181192 nt
    Select Tool
    Polypeptide UniProtKB:A0A2R8PZ52 (1) 2838 aa
    Sequence Information (all 41)
    ORTHOLOGY for mgaa ( Chr: 17 )
    CITATIONS (29)