ZFIN ID: ZDB-GENE-030513-1
Gene Name: prolactin
Gene Symbol: prl
Sequence Ontology ID : SO:0000704

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Previous Names: prl1 (1), zgc:110500

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(Including Attributions)
Location: Chr: 3 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 46 figures from 23 publications
Wild-type Stages, Structures: Segmentation:26+ somites (22.0h-24.0h) to Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth)
  adenohypophyseal placode, adenohypophysis, anatomical structure, hypophysis (all 10) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb182 Small Deletion Unknown Unknown TALEN
ihb183 Small Deletion Unknown Unknown TALEN
sa6902 Point Mutation Unknown Splice Site ENU
sa26090 Point Mutation Unknown Splice Site ENU
Targeting reagents: MO1-prl (1), MO2-prl (1), TALEN1-prl (1)
PHENOTYPE
Data: 3 figures from Nguyen et al., 2009
Observed in: apoptotic DNA fragmentation, apoptotic process, brain, immature eye
DISEASE ASSOCIATED WITH prl HUMAN ORTHOLOGNo data available
GENE ONTOLOGY
Ontology GO Term
Biological Process negative regulation of apoptotic process (more)
Cellular Component extracellular region (more)
Molecular Function hormone activity (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001400 (1)
  • InterPro:IPR009079 (1)
  • InterPro:IPR018116 (1)
  • PROSITE:PS00266 (1)
  • PROSITE:PS00338 (1)
  • Pfam:PF00103 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA prl-001 (1) 1399
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM prl
    TgBAC(prl:RFP)
    MARKER RELATIONSHIPS
    prlContained in: [BAC] DKEY-16P21 (1) (order this)
    prlEncodes: [cDNA] MGC:110500 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_181437 (1) 1425bp
    Genomic GenBank:BX511021 (1) 235632bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1R0Y2 (1) 210aa
    Sequence Clusters UniGene:88633 (1)
    Sequence Information (all 12)
    OTHER prl GENE PAGES
  • Alliance (1)
  • Gene:791526 (1)
  • VEGA:OTTDARG00000019973 (1)
  • Ensembl(GRCz10):ENSDARG00000037946 (1)
  • ORTHOLOGY for prl (Chr: 3)
    CITATIONS (61)