ZFIN ID: ZDB-GENE-030421-3
Gene Name: phospholipase C, gamma 1
Gene Symbol: plcg1
Sequence Ontology ID : SO:0000704

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Previous Names: dead beat, ded, fj46f04, wu:fj46f04 (1), wu:fj57a05

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(Including Attributions)
Location: Chr: 23 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have phosphatidylinositol phospholipase C activity; involved in several processes, including blood vessel development, fin regeneration, and hemopoiesis; orthologous to human PLCG1  ...
GENE EXPRESSION
All Expression Data: 11 figures from 6 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi2335Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • hi3479Tg Transgenic Insertion Unknown Unknown DNA
    la022620Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • m582 Point Mutation Unknown Unknown ENU
    rj100 Point Mutation Unknown Premature Stop ENU
    t26480 Point Mutation Unknown Unknown
  • European Zebrafish Resource Center (EZRC) (order this)
  • y10 Point Mutation Acceptor Splice Site Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • y13 Point Mutation Unknown Missense ENU
    y15 Point Mutation Unknown Unknown ENU
    y16 Point Mutation Unknown Unknown ENU
    y18 Point Mutation Donor Splice Site Unknown
    y19 Unknown Unknown Unknown ENU
    Targeting reagents:
    PHENOTYPE
    Data: 26 figures from 14 publications
    Observed in:
    DISEASE ASSOCIATED WITH plcg1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH plcg1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process angiogenesis (more)
    Molecular Function hydrolase activity (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000008 (1)
  • InterPro:IPR000909 (1)
  • InterPro:IPR000980 (1)
  • InterPro:IPR001192 (1)
  • InterPro:IPR001452 (1)
  • InterPro:IPR001711 (1)
  • InterPro:IPR001849 (1)
  • InterPro:IPR011992 (1)
  • InterPro:IPR011993 (1)
  • InterPro:IPR016279 (1)
  • InterPro:IPR017946 (1)
  • InterPro:IPR018247 (1)
  • InterPro:IPR028380 (1)
  • InterPro:IPR035023 (1)
  • InterPro:IPR035024 (1)
  • InterPro:IPR035724 (1)
  • InterPro:IPR035892 (1)
  • InterPro:IPR036028 (1)
  • InterPro:IPR036860 (1)
  • PROSITE:PS00018 (1)
  • PROSITE:PS50001 (1)
  • PROSITE:PS50002 (1)
  • PROSITE:PS50003 (1)
  • PROSITE:PS50004 (1)
  • PROSITE:PS50008 (1)
  • Pfam:PF00017 (1)
  • Pfam:PF00018 (1)
  • Pfam:PF00168 (1)
  • Pfam:PF00387 (1)
  • Pfam:PF00388 (1)
  • EC:3.1.4.11 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA plcg1-001 (1) 5161
    plcg1-002 (1) 407
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM plcg1 No data available
    MARKER RELATIONSHIPS
    plcg1Contained in: [Fosmid] CH1073-154M12 (1) (order this), CH1073-161C3 (1) (order this), CH1073-213L17 (1) (order this)
    plcg1Encodes: [EST] fj46f04 (1), fj57a05
    [cDNA] MGC:194052 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_194407 (1) 4103bp
    Genomic GenBank:CU633907 (1) 38805bp
    Select Tool
    Polypeptide UniProtKB:B3DH74 (1) 1312aa
    Sequence Clusters UniGene:149516 (1)
    Sequence Information (all 41)
    OTHER plcg1 GENE PAGES
  • Alliance (1)
  • Gene:373867 (1)
  • VEGA:OTTDARG00000030387 (1)
  • Ensembl(GRCz11):ENSDARG00000038442 (2)
  • ORTHOLOGY for plcg1 (Chr: 23)
    CITATIONS (68)