Gene

plcg1

ID
ZDB-GENE-030421-3
Name
phospholipase C, gamma 1
Symbol
plcg1 Nomenclature History
Previous Names
  • dead beat
  • ded
  • fj46f04
  • wu:fj46f04 (1)
  • wu:fj57a05
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have phosphatidylinositol phospholipase C activity. Involved in several processes, including blood vessel morphogenesis; fin regeneration; and hemopoiesis. Is expressed in brain; intermediate cell mass of mesoderm; ovary; pericardial region; and vasculature. Orthologous to human PLCG1 (phospholipase C gamma 1).
Genome Resources
Note
None
Expression
All Expression Data
11 figures from 6 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
28 figures from 16 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With plcg1 Human Ortholog
No data available
Associated With plcg1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR018247 EF-Hand 1, calcium-binding site
Domain IPR000008 C2 domain
Domain IPR000909 Phosphatidylinositol-specific phospholipase C, X domain
Domain IPR000980 SH2 domain
Domain IPR001452 SH3 domain
Domain IPR001711 Phospholipase C, phosphatidylinositol-specific, Y domain
Domain IPR001849 Pleckstrin homology domain
Domain IPR035023 PLC-gamma, C-terminal SH2 domain
Domain IPR035024 PLC-gamma, N-terminal SH2 domain
Domain IPR035724 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, SH3 domain
Family IPR001192 Phosphoinositide phospholipase C family
Family IPR016279 Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma
Family IPR028380 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
Homologous_superfamily IPR011992 EF-hand domain pair
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
Homologous_superfamily IPR035892 C2 domain superfamily
Homologous_superfamily IPR036028 SH3-like domain superfamily
Homologous_superfamily IPR036860 SH2 domain superfamily
Domain Details Per Protein
Protein Length 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, SH3 domain C2 domain C2 domain superfamily EF-Hand 1, calcium-binding site EF-hand domain pair PH-like domain superfamily Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma Phosphatidylinositol-specific phospholipase C, X domain Phosphoinositide phospholipase C family Phospholipase C, phosphatidylinositol-specific, Y domain PLC-gamma, C-terminal SH2 domain PLC-gamma, N-terminal SH2 domain PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily Pleckstrin homology domain SH2 domain SH2 domain superfamily SH3 domain SH3-like domain superfamily
UniProtKB:F1QLX2 1020
UniProtKB:Q804J5 28
UniProtKB:Q804J4 50
UniProtKB:X1WH04 75
UniProtKB:B3DH74 1312
UniProtKB:Q804J6 1312
Transcripts
Genome Browsers
Interactions and Pathways
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations