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General Information
ZIRC
ZFIN ID: ZDB-GENE-030328-41
Gene Name: iodothyronine deiodinase 1
Gene Symbol: dio1
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: Deio1 (1), cb685 (1), zgc:92323

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(Including Attributions)
Location: Chr: 8 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have thyroxine 5'-deiodinase activity. Involved in regulation of neural retina development. Predicted to localize to the integral component of membrane. Orthologous to human DIO1  ...
GENE EXPRESSION
All Expression Data: 7 figures from 6 publications
Directly Submitted Expression Data: 2 figures (4 images) from Thisse et al., 2001 [cb685]
Wild-type Stages, Structures: Gastrula:75%-epiboly (8.0h-9.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents:
PHENOTYPE No data available
DISEASE ASSOCIATED WITH dio1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH dio1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of neural retina development (more)
Cellular Component integral component of membrane (more)
Molecular Function oxidoreductase activity (more)
GO Terms (all 8)
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA dio1-201 (1) 1474
GENE PRODUCT DESCRIPTION
INTERACTIONS AND PATHWAYS
ANTIBODIESNo data available
PLASMIDSNo data available
CONSTRUCTS WITH SEQUENCES FROM dio1 No data available
MARKER RELATIONSHIPS
dio1Contained in: [BAC] DKEY-30K23 (1) (order this)
dio1Encodes: [EST] cb685 (1) (order this)
[cDNA] MGC:92323 (1) (order this), MGC:174383 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001007283 (1) 1417bp
Genomic GenBank:CR759953 (1) 162332bp
Select Tool
Polypeptide UniProtKB:A9JRP6 (1) 254aa
Sequence Clusters UniGene:76544 (1)
Sequence Information (all 29)
ORTHOLOGY for dio1 (Chr: 8)
CITATIONS (103)