Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030327-7
Gene Name: selenoprotein N, 1
Gene Symbol: sepn1
Previous Names: cb686 (1), wu:fb06g01, wu:fb73d02, wu:fv41b08, zgc:101091
Location: Chr: 17   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 11 figures from 3 publications
Directly Submitted Expression Data: 6 figures (26 images) from Thisse et al., 2001 [cb686]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
  adaxial cell, anterior axial hypoblast, axis, central nervous system (all 24) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Knockdown reagents: MO1-sepn1 (1), MO2-sepn1 (1), MO3-sepn1 (1), MO4-sepn1 (1), MO5-sepn1 (1) (all 6) expand
PHENOTYPE
Data: 9 figures from 2 publications
Observed in: heart, muscle cell sarcomere, myoseptum, myotome (all 11) expand

Phenotype of Human Orthologue OMIM Phenotype ID
Muscular dystrophy, rigid spine, 1 602771
Myopathy, congenital, with fiber-type disproportion 255310
GENE ONTOLOGY
Ontology GO Term
Biological Process skeletal muscle fiber development (more)
Cellular Component integral component of membrane (more)
GO Terms (all 3)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA sepn1-001 (1) 2873
ncRNA sepn1-002 (1) 609
sepn1-003 (1) 513
GENE PRODUCT DESCRIPTION
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM sepn1 No data available
SEGMENT (CLONE AND PROBE) RELATIONSHIPS
sepn1 Contained in: [BAC] CH211-15D5 (1) (order this), CH211-247C16 (order this)
sepn1 Encodes: [EST] cb686 (1) (order this), fb06g01, fb73d02, fv41b08
[cDNA] MGC:101091 (order this), MGC:174730 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001004294 (1) 2896 bp
Genomic GenBank:CR626962 (1) 117015 bp
Select Tool
Polypeptide UniProtKB:E7FD15 (1) 557 aa
Sequence Clusters UniGene:17178 (1)
Sequence Information (all 36)
OTHER sepn1 GENE PAGES
  • Gene:352914 (1)
  • VEGA:OTTDARG00000028713 (1)
  • Ensembl(Zv9):ENSDARG00000033616 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish sepn1 17  
    Human SEPN1 1 (1p36.13)
  • OMIM:606210
  • Gene:57190
  • Mouse Sepn1 4 ( 66.85 cM)
  • MGI:2151208
  • Gene:74777
  • Orthology Details
    CITATIONS (21)