header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030319-6
Gene Name: purinergic receptor P2X, ligand-gated ion channel, 7
Gene Symbol: p2rx7
Sequence Ontology ID : SO:0001217

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name:

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 8 Mapping Details/Browsers
AUTOMATED DESCRIPTION
Exhibits extracellularly ATP-gated cation channel activity. Involved in calcium ion import across plasma membrane and macrophage chemotaxis. Localizes to the plasma membrane. Is expressed in brain;  ...
GENE EXPRESSION
All Expression Data: 4 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu706]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa17772 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21329 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • xt26 Small Deletion Unknown Unknown CRISPR
    xt28 Indel Unknown Unknown CRISPR
    Targeting reagents:
    PHENOTYPE
    Data: Fig. S2 from Ogryzko et al., 2014
    Observed in:
    DISEASE ASSOCIATED WITH p2rx7 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH p2rx7 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process calcium ion import across plasma membrane (more)
    Cellular Component plasma membrane (more)
    Molecular Function ATP-gated ion channel activity (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001429 (1)
  • InterPro:IPR003050 (1)
  • InterPro:IPR027309 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA p2rx7-201 (1) 1877
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM p2rx7 No data available
    MARKER RELATIONSHIPS
    p2rx7 Contained in: [BAC] CH211-42D10 (1) (order this)
    p2rx7 Encodes: [EST] eu706 (1)
    [cDNA] MGC:194725 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_198984 (1) 1860 bp
    Genomic GenBank:BX640478 (1) 191201 bp
    Select Tool
    Polypeptide UniProtKB:A0A2R8QGJ4 (1) 597 aa
    Sequence Clusters UniGene:89527 (1)
    Sequence Information (all 16)
    ORTHOLOGY for p2rx7 ( Chr: 8 )
    CITATIONS (29)