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Gene

usp10

ID
ZDB-GENE-030219-132
Name
ubiquitin specific peptidase 10
Symbol
usp10 Nomenclature History
Previous Names
  • id:ibd1190
  • wu:fc19h08
  • wu:fc76g05
  • wu:fi11g01
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to enable cysteine-type endopeptidase activity and thiol-dependent deubiquitinase. Predicted to be involved in DNA damage response, signal transduction by p53 class mediator; protein deubiquitination; and regulation of autophagy. Predicted to act upstream of or within DNA repair; autophagy; and ubiquitin-dependent protein catabolic process. Predicted to be active in cytosol and nucleus. Is expressed in immature eye and optic tectum. Orthologous to human USP10 (ubiquitin specific peptidase 10).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Tse et al., 2009
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With usp10 Human Ortholog
No data available
Associated With usp10 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018200 Ubiquitin specific protease, conserved site
Domain IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase
Domain IPR009818 Ataxin-2, C-terminal
Domain IPR028889 Ubiquitin specific protease domain
Family IPR028767 Ubiquitin carboxyl-terminal hydrolase 10
Homologous_superfamily IPR038765 Papain-like cysteine peptidase superfamily
Domain Details Per Protein
Protein Length Ataxin-2, C-terminal Papain-like cysteine peptidase superfamily Peptidase C19, ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase 10 Ubiquitin specific protease, conserved site Ubiquitin specific protease domain
UniProtKB:A0A2R8Q9M8 898
UniProtKB:A0A2R8PWQ0 878
UniProtKB:A0A0R4IK19 220
UniProtKB:A0A0R4IVE2 865
UniProtKB:A0A0R4IQ47 35
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations