ZFIN ID: ZDB-GENE-030131-9923
Gene Name: helicase, lymphoid specific
Gene Symbol: hells
Sequence Ontology ID : SO:0000704

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Previous Names: cb65 (1), im:6911667, sb:cb65, sb:cb749

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(Including Attributions)
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 18 figures from 3 publications
Directly Submitted Expression Data: 3 figures (3 images) from Thisse et al., 2004 [IMAGE:6911667]
  6 figures (18 images) from Thisse et al., 2001 [cb749]
  6 figures (7 images) from Thisse et al., 2001 [cb65]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
  alar plate midbrain region, central nervous system, forebrain, hindbrain (all 19) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents: MO1-hells (1), MO2-hells (1), MO3-hells (1)
PHENOTYPE
Data: Fig. 1 from Dunican et al., 2015
Observed in: brain, caudal fin, DNA methylation, embryo development (all 6) expand
DISEASE ASSOCIATED WITH hells HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
immunodeficiency-centromeric instability-facial anomalies syndrome 4 Immunodeficiency-centromeric instability-facial anomalies syndrome 4 616911
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of DNA methylation (more)
Molecular Function ATP binding (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000330 (1)
  • InterPro:IPR001650 (1)
  • InterPro:IPR014001 (1)
  • InterPro:IPR027417 (1)
  • InterPro:IPR031053 (1)
  • PROSITE:PS51192 (1)
  • PROSITE:PS51194 (1)
  • Pfam:PF00176 (1)
  • Pfam:PF00271 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA hells-001 (1) 3287
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM hells No data available
    MARKER RELATIONSHIPS
    hellsContained in: [BAC] CH211-160I12 (1) (order this), CH211-250C4 (1) (order this)
    hellsEncodes: [EST] cb65 (1) (order this), cb749 (1) (order this), IMAGE:6911667 (1) (order this)
    [cDNA] MGC:198135 (1) (order this), MGC:198137 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001037101 (1) 3170bp
    Genomic GenBank:AL935288 (1) 181644bp
    Select Tool
    Polypeptide UniProtKB:B7ZD98 (1) 853aa
    Sequence Clusters UniGene:75180 (1)
    Sequence Information (all 36)
    OTHER hells GENE PAGES
  • Alliance (1)
  • Gene:553328 (1)
  • VEGA:OTTDARG00000020679 (1)
  • Ensembl(GRCz10):ENSDARG00000057738 (1)
  • ORTHOLOGY for hells (Chr: 13)
    CITATIONS (24)