ZFIN ID: ZDB-GENE-030131-9923
Gene Name: helicase, lymphoid specific
Gene Symbol: hells    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: cb65 (1), im:6911667, sb:cb65, sb:cb749

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have DNA binding activity and DNA-dependent ATPase activity. Involved in regulation of DNA methylation. Predicted to localize to nucleus. Is expressed in several structures, including alar plate midbrain region; central nervous system; immature eye; margin; and pectoral fin musculature. Human ortholog(s) of this gene implicated in immunodeficiency-centromeric instability-facial anomalies syndrome 4. Orthologous to human HELLS (helicase, lymphoid specific).
Genome Resources: Alliance (1),  Gene:553328 (1),  Ensembl(GRCz11):ENSDARG00000057738 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-hells N/A 1
MO2-hells N/A 1
MO3-hells N/A 1
DISEASE ASSOCIATED WITH hells HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
immunodeficiency-centromeric instability-facial anomalies syndrome 4 Alliance Immunodeficiency-centromeric instability-facial anomalies syndrome 4 616911
DISEASE ASSOCIATED WITH hells VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of DNA methylation (more)
Cellular Component nucleus (more)
Molecular Function ATP binding (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA hells-201 (1)    Ensembl 3287
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM hells No data available
MARKER RELATIONSHIPS
hells Contained in: [BAC] CH211-160I12 (1), CH211-250C4 (1)
hells Encodes: [EST] cb65 (1) (order this), cb749 (1) (order this), IMAGE:6911667 (1)
[cDNA] MGC:198135 (1), MGC:198137 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001037101 (1) 3170 nt
Genomic GenBank:AL935288 (1) 181644 nt
Select Tool
Polypeptide UniProtKB:B7ZD98 (1) 853 aa
Sequence Information (all 36)
ORTHOLOGY for hells ( Chr: 13 )
CITATIONS (27)