ZFIN ID: ZDB-GENE-030131-9875
Gene Name: kelch-like family member 41b
Gene Symbol: klhl41b    Nomenclature History

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Previous Names: cb52 (1), kbtbd10, kbtbd10b, sarcosin (1), sb:cb52, wu:fb24f05, wu:fc15e07

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Involved in sarcomere organization and skeletal muscle fiber development. Predicted to localize to cytoskeleton and sarcoplasmic reticulum membrane. Is expressed in adaxial cell; musculature system; pericardial region; and somite. Human ortholog(s) of this gene implicated in nemaline myopathy 9. Orthologous to human KLHL41 (kelch like family member 41).
Genome Resources: Alliance (1),  Gene:321064 (1),  Ensembl(GRCz11):ENSDARG00000006757 (2)
GENE EXPRESSION
All Expression Data: 6 figures from 2 publications
Directly Submitted Expression Data: 5 figures (6 images) from Thisse et al., 2001 [cb52]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa26661 Point Mutation Unknown Splice Site ENU
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-klhl41b N/A 1
MO2-klhl41b N/A 1
DISEASE ASSOCIATED WITH klhl41b HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
nemaline myopathy 9 Alliance Nemaline myopathy 9 615731
DISEASE ASSOCIATED WITH klhl41b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process sarcomere organization (more)
Cellular Component cytoplasm (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS No data available
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM klhl41b No data available
MARKER RELATIONSHIPS
klhl41b Contains: [SNP] rs3727940 (1)
klhl41b Encodes: [EST] cb52 (1) (order this), fb24f05, fc15e07
[cDNA] MGC:63560 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_198979 (1) 2297 nt
Polypeptide UniProtKB:F1QEG2 (1) 605 aa
Sequence Information (all 13)
ORTHOLOGY for klhl41b ( Chr: 6 )
CITATIONS (33)