Gene

ctsf

ID
ZDB-GENE-030131-9831
Name
cathepsin F
Symbol
ctsf Nomenclature History
Previous Names
  • cb420 (1)
  • sb:cb420
  • zgc:153093
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in cellular protein catabolic process. Predicted to localize to extracellular space and lysosome. Is expressed in mesoderm; nervous system; neural tube; solid lens vesicle; and ventral mesenchyme. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 13. Orthologous to human CTSF (cathepsin F).
Genome Resources
Note
None
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ctsf Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
neuronal ceroid lipofuscinosis 13 Alliance Ceroid lipofuscinosis, neuronal, 13, Kufs type 615362
Associated With ctsf Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR000169 Cysteine peptidase, cysteine active site
Active_site IPR025660 Cysteine peptidase, histidine active site
Domain IPR000010 Cystatin domain
Domain IPR000668 Peptidase C1A, papain C-terminal
Domain IPR013201 Cathepsin propeptide inhibitor domain (I29)
Domain IPR039417 Papain-like cysteine endopeptidase
Homologous_superfamily IPR038765 Papain-like cysteine peptidase superfamily
Domain Details Per Protein
Protein Length Cathepsin propeptide inhibitor domain (I29) Cystatin domain Cysteine peptidase, cysteine active site Cysteine peptidase, histidine active site Papain-like cysteine endopeptidase Papain-like cysteine peptidase superfamily Peptidase C1A, papain C-terminal
UniProtKB:Q08CH0 473
UniProtKB:B2GT35 473
UniProtKB:F1RE14 473
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations