Gene
kdm7aa
- ID
- ZDB-GENE-030131-9829
- Name
- lysine (K)-specific demethylase 7Aa
- Symbol
- kdm7aa Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Exhibits histone demethylase activity (H3-K27 specific) and histone demethylase activity (H3-K9 specific). Involved in histone H3-K27 demethylation; histone H3-K9 demethylation; and midbrain development. Predicted to localize to nucleus. Is expressed in several structures, including anterior axial hypoblast; immature eye; margin; mesoderm; and nervous system. Human ortholog(s) of this gene implicated in melanoma. Orthologous to human KDM7A (lysine demethylase 7A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb414 (18 images)
- IMAGE:7139974 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | JmjC domain | Jumonji, helical domain | Zinc finger, FYVE/PHD-type | Zinc finger, PHD-finger | Zinc finger, PHD-type | Zinc finger, PHD-type, conserved site |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q32PK5
|
188 | ||||||
|
UniProtKB:A0A2R8RKB3
|
837 | ||||||
|
UniProtKB:Q5RHD0
|
188 | ||||||
|
UniProtKB:Q5RHD1
|
875 | ||||||
|
UniProtKB:E7FCP4
|
613 |
| Type | Name | Length (nt) | Analysis |
|---|---|---|---|
| mRNA |
kdm7aa-201
(1)
|
1848 nt | |
| mRNA |
kdm7aa-202
(1)
|
841 nt |
Interactions and Pathways
No data available
Plasmids
No data available