Gene

ftsj3

ID

ZDB-GENE-030131-9828

Name

FtsJ RNA 2'-O-methyltransferase 3

Symbol

ftsj3 Nomenclature History

Previous Names

ftsj
cb410 (1)
sb:cb410
wu:fa08a09

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Predicted to have rRNA (guanine) methyltransferase activity and rRNA (uridine-2'-O-)-methyltransferase activity. Predicted to be involved in maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); and rRNA methylation. Predicted to localize to nucleolus and preribosome, large subunit precursor. Is expressed in several structures, including digestive system; immature eye; mesoderm; midbrain; and musculature system. Orthologous to human FTSJ3 (FtsJ RNA 2'-O-methyltransferase 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2001

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

cb410 (20 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ftsj3 Human Ortholog

No data available

Associated With ftsj3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002877	Ribosomal RNA methyltransferase, FtsJ domain
Domain	IPR012920	Ribosomal RNA methyltransferase, SPB1-like, C-terminal
Domain	IPR024576	Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381
Family	IPR015507	Ribosomal RNA large subunit methyltransferase E
Family	IPR028589	AdoMet-dependent rRNA methyltransferase SPB1-like
Homologous_superfamily	IPR029063	S-adenosyl-L-methionine-dependent methyltransferase superfamily