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ZIRC
ZFIN ID: ZDB-GENE-030131-9826
Gene Name: ATP-binding cassette, sub-family A (ABC1), member 1B
Gene Symbol: abca1b    Nomenclature History

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Previous Names: im:7136239, sb:cb407, wu:fa07e06, zgc:171581

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Predicted to have ATPase-coupled transmembrane transporter activity and lipid transporter activity. Predicted to be involved in phospholipid efflux. Predicted to localize to the intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in Alzheimer's disease; coronary artery disease; hypolipoproteinemia (multiple); obesity; and type 2 diabetes mellitus. Is expressed in several structures, including hypochord; mesoderm; notochord; solid lens vesicle; and yolk syncytial layer. Orthologous to human ABCA1 (ATP binding cassette subfamily A member 1).
Genome Resources: Alliance (1),  Gene:100136868 (1),  Ensembl(GRCz11):ENSDARG00000079009 (2)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH abca1b HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Tangier disease Alliance Tangier disease 205400
HDL deficiency, familial, 1 604091
DISEASE ASSOCIATED WITH abca1b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process transmembrane transport (more)
Cellular Component integral component of membrane (more)
Molecular Function ATPase activity (more)
GO Terms (all 13)
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA abca1b-201 (1)    Ensembl 8271
abca1b-203 (1)    Ensembl 1614
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM abca1b No data available
MARKER RELATIONSHIPS
abca1b Contained in: [BAC] CH211-198I6 (1) (order this)
abca1b Encodes: [EST] cb407 (1) (order this), fa07e06, IMAGE:7136239 (1) (order this)
[cDNA] MGC:171581 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001114586 (1) 1617 bp
Genomic GenBank:CT009487 (1) 195244 bp
Select Tool
Polypeptide UniProtKB:E7F2Y6 (1) 2282 aa
Sequence Clusters UniGene:27189 (1)
Sequence Information (all 21)
ORTHOLOGY for abca1b ( Chr: 14 )
CITATIONS (31)