ZFIN ID: ZDB-GENE-030131-9826
Gene Name: ATP-binding cassette, sub-family A (ABC1), member 1B
Gene Symbol: abca1b
Previous Names: im:7136239, sb:cb407, wu:fa07e06, zgc:171581
Location: Chr: 14   Details
Nomenclature History
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (11 images) from Thisse et al., 2001 [cb407]
  7 figures (7 images) from Thisse et al., 2004 [IMAGE:7136239]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  floor plate, hypochord, mesoderm, notochord (all 9) expand
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: la019103Tg, sa16400, sa18382, sa22420
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
HDL deficiency, type 2 604091
Tangier disease 205400
{Coronary artery disease in familial hypercholesterolemia, protection against} 143890
GENE ONTOLOGY
Ontology GO Term
Biological Process transport (more)
Cellular Component integral component of membrane (more)
Molecular Function ATP binding (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003439 (1)
  • InterPro:IPR003593 (1)
  • InterPro:IPR017871 (1)
  • InterPro:IPR026082 (1)
  • InterPro:IPR027417 (1)
  • PROSITE:PS00211 (1)
  • PROSITE:PS50893 (1)
  • Pfam:PF00005 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA abca1b-001 (1) 8271
    ottdart00000060118 (1) 1614
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM abca1b No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    abca1b Contained in: [BAC] CH211-198I6 (1) (order this)
    abca1b Encodes: [EST] cb407 (1) (order this), fa07e06, IMAGE:7136239 (1) (order this)
    [cDNA] MGC:171581 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001114586 (1) 8390 bp
    Genomic GenBank:CT009487 (1) 195244 bp
    Select Tool
    Polypeptide UniProtKB:E7F2Y6 (1) 2282 aa
    Sequence Clusters UniGene:27189 (1)
    Sequence Information (all 21)
    OTHER abca1b GENE PAGES
  • Gene:100136868 (1)
  • VEGA:OTTDARG00000034940 (1)
  • Ensembl(Zv9):ENSDARG00000079009 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish abca1b 14  
    Human ABCA1 9 (9q31.1)
  • OMIM:600046
  • Gene:19
  • Mouse Abca1 4 ( 28.57 cM)
  • MGI:99607
  • Gene:11303
  • Orthology Details
    CITATIONS (19)