Gene

abca1b

ID
ZDB-GENE-030131-9826
Name
ATP-binding cassette, sub-family A (ABC1), member 1B
Symbol
abca1b Nomenclature History
Previous Names
  • im:7136239
  • sb:cb407
  • wu:fa07e06
  • zgc:171581
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have ATPase-coupled transmembrane transporter activity; phosphatidylcholine floppase activity; and phosphatidylserine floppase activity. Predicted to be involved in phospholipid efflux. Predicted to localize to intracellular membrane-bounded organelle. Is expressed in several structures, including hypochord; mesoderm; notochord; solid lens vesicle; and yolk syncytial layer. Human ortholog(s) of this gene implicated in Alzheimer's disease; coronary artery disease; hypolipoproteinemia (multiple); obesity; and type 2 diabetes mellitus. Orthologous to human ABCA1 (ATP binding cassette subfamily A member 1).
Genome Resources
Note
None
Expression
All Expression Data
16 figures from 5 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With abca1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Tangier disease Alliance Tangier disease 205400
HDL deficiency, familial, 1 604091
Associated With abca1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017871 ABC transporter, conserved site
Domain IPR003439 ABC transporter-like
Domain IPR003593 AAA+ ATPase domain
Family IPR026082 ABC transporter A
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length AAA+ ATPase domain ABC transporter A ABC transporter, conserved site ABC transporter-like P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A8KB58 142
UniProtKB:E7F2Y6 2282
UniProtKB:F8W2X9 2271
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations