Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030131-9826
Gene Name: ATP-binding cassette, sub-family A (ABC1), member 1B
Gene Symbol: abca1b
Previous Names: im:7136239, sb:cb407, wu:fa07e06, zgc:171581
Location: Chr: 14   Details
Nomenclature History
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (11 images) from Thisse et al., 2001 [cb407]
  7 figures (7 images) from Thisse et al., 2004 [IMAGE:7136239]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  floor plate, hypochord, mesoderm, notochord (all 9) expand
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: la019103Tg, sa16400, sa18382, sa22420
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
HDL deficiency, type 2 604091
Tangier disease 205400
{Coronary artery disease in familial hypercholesterolemia, protection against} 143890
GENE ONTOLOGY
Ontology GO Term
Cellular Component cellular_component (more)
Molecular Function ATP binding (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003439 (1)
  • InterPro:IPR003593 (1)
  • InterPro:IPR017871 (1)
  • InterPro:IPR026082 (1)
  • InterPro:IPR027417 (1)
  • PROSITE:PS00211 (1)
  • PROSITE:PS50893 (1)
  • Pfam:PF00005 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA abca1b-001 (1) 6290
    abca1b-002 (1) 1614
    abca1b-003 (1) 751
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM abca1b No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    abca1b Contained in: [BAC] CH211-198I6 (1) (order this)
    abca1b Encodes: [EST] cb407 (1) (order this), fa07e06, IMAGE:7136239 (1) (order this)
    [cDNA] MGC:171581 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001114586 (1) 8390 bp
    Genomic GenBank:CT009487 (1) 195244 bp
    Select Tool
    Polypeptide UniProtKB:E7F2Y6 (1) 2282 aa
    Sequence Clusters UniGene:27189 (1)
    Sequence Information (all 23)
    OTHER abca1b GENE PAGES
  • Gene:100136868 (1)
  • VEGA:OTTDARG00000034940 (1)
  • Ensembl(Zv9):ENSDARG00000079009 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish abca1b 14  
    Human ABCA1 9 (9q31.1)
  • OMIM:600046
  • Gene:19
  • Mouse Abca1 4 ( 28.57 cM)
  • MGI:99607
  • Gene:11303
  • Orthology Details
    CITATIONS (20)