ZFIN ID: ZDB-GENE-030131-9826
Gene Name: ATP-binding cassette, sub-family A (ABC1), member 1B
Gene Symbol: abca1b
Previous Names: im:7136239, sb:cb407, wu:fa07e06, zgc:171581
Location: Chr: 14 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 14 figures from 3 publications
Directly Submitted Expression Data: 6 figures (11 images) from Thisse et al., 2001 [cb407]
  7 figures (7 images) from Thisse et al., 2004 [IMAGE:7136239]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth)
  floor plate, hypochord, mesoderm, notochord (all 10) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
la019103Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16400 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa18382 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa22420 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH abca1b HUMAN ORTHOLOG 
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    familial hypercholesterolemia {Coronary artery disease in familial hypercholesterolemia, protection against} 143890
    Tangier disease Tangier disease 205400
    HDL deficiency, type 2 604091
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process cholesterol efflux (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003439 (1)
  • InterPro:IPR003593 (1)
  • InterPro:IPR017871 (1)
  • InterPro:IPR026082 (1)
  • InterPro:IPR027417 (1)
  • InterPro:IPR030365 (1)
  • PROSITE:PS00211 (1)
  • PROSITE:PS50893 (1)
  • Pfam:PF00005 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA abca1b-001 (1) 8271
    ottdart00000060118 (1) 1614
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM abca1b No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    abca1bContained in: [BAC] CH211-198I6 (1) (order this)
    abca1bEncodes: [EST] cb407 (1) (order this), fa07e06, IMAGE:7136239 (1) (order this)
    [cDNA] MGC:171581 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001114586 (1) 8390bp
    Genomic GenBank:CT009487 (1) 195244bp
    Select Tool
    Polypeptide UniProtKB:E7F2Y6 (1) 2282aa
    Sequence Clusters UniGene:27189 (1)
    Sequence Information (all 20)
    OTHER abca1b GENE PAGES 
  • Gene:100136868 (1)
  • VEGA:OTTDARG00000034940 (1)
  • Ensembl(GRCz10):ENSDARG00000079009 (1)
  • ORTHOLOGY for abca1b (Chr: 14) 
    Species Symbol Chromosome Accession # Evidence
    Human ABCA1 9
  • Gene:19
  • OMIM:600046
  • HGNC:29
  • Amino acid sequence comparison (3)
    Conserved genome location (synteny) (1)
    Mouse Abca1 4
  • MGI:99607
  • Gene:11303
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (23)