Gene
lama5
- ID
- ZDB-GENE-030131-9823
- Name
- laminin, alpha 5
- Symbol
- lama5 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to have extracellular matrix structural constituent and integrin binding activity. Involved in cell-cell adhesion; fin morphogenesis; and protein localization. Predicted to localize to laminin-5 complex. Is expressed in several structures, including axial mesoderm; endoderm; nervous system; pectoral fin bud; and pharynx. Orthologous to human LAMA5 (laminin subunit alpha 5).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 34 figures from 13 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb402 (39 images)
- IMAGE:7138247 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- 19 figures from 7 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
bent bone dysplasia syndrome 2 | Alliance | ?Bent bone dysplasia syndrome 2 | 620076 |
Nephrotic syndrome, type 26 | 620049 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR000034 | Laminin IV |
Domain | IPR000742 | EGF-like domain |
Domain | IPR001791 | Laminin G domain |
Domain | IPR002049 | Laminin-type EGF domain |
Domain | IPR008211 | Laminin, N-terminal |
Domain | IPR009254 | Laminin alpha, domain I |
Domain | IPR010307 | Laminin domain II |
Family | IPR050440 | Laminin/Netrin Extracellular Matrix |
Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
Domain Details Per Protein
Protein | Length | Concanavalin A-like lectin/glucanase domain superfamily | EGF-like domain | Laminin alpha, domain I | Laminin domain II | Laminin G domain | Laminin IV | Laminin/Netrin Extracellular Matrix | Laminin, N-terminal | Laminin-type EGF domain |
---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M3AY57
|
3662 | |||||||||
UniProtKB:A0A8M3ANE8
|
3665 | |||||||||
UniProtKB:Q2Q1W5
|
3664 |
Interactions and Pathways
No data available
Plasmids
No data available