Gene

lama5

ID

ZDB-GENE-030131-9823

Name

laminin, alpha 5

Symbol

lama5 Nomenclature History

Previous Names

fra (1)
cb402 (1)
fransen (1)
im:7138247
sb:cb402
unm m538
wu:fb81a10

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

Predicted to have integrin binding activity. Involved in cell-cell adhesion; fin morphogenesis; and protein localization. Predicted to localize to laminin-5 complex. Is expressed in several structures, including axial mesoderm; endoderm; nervous system; pectoral fin bud; and pharynx. Orthologous to human LAMA5 (laminin subunit alpha 5).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

32 figures from 11 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

cb402 (39 images)
IMAGE:7138247 (10 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 18 figures from 6 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With lama5 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Nephrotic syndrome, type 26	620049
		?Bent bone dysplasia syndrome 2	620076

Associated With lama5 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000034	Laminin IV
Domain	IPR000742	EGF-like domain
Domain	IPR001791	Laminin G domain
Domain	IPR002049	Laminin-type EGF domain
Domain	IPR008211	Laminin, N-terminal
Domain	IPR009254	Laminin alpha, domain I
Domain	IPR010307	Laminin domain II
Homologous_superfamily	IPR013320	Concanavalin A-like lectin/glucanase domain superfamily