Gene
lama5
- ID
- ZDB-GENE-030131-9823
- Name
- laminin, alpha 5
- Symbol
- lama5 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable integrin binding activity. Acts upstream of or within cell-cell adhesion; fin morphogenesis; and protein localization. Predicted to be located in extracellular region and membrane. Predicted to be part of laminin-5 complex. Predicted to be active in basement membrane. Is expressed in several structures, including axial mesoderm; endoderm; nervous system; pectoral fin bud; and pharynx. Human ortholog(s) of this gene implicated in familial nephrotic syndrome. Orthologous to human LAMA5 (laminin subunit alpha 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 32 figures from 11 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb402 (39 images)
- IMAGE:7138247 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- 18 figures from 6 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR000034 | Laminin IV |
Domain | IPR000742 | EGF-like domain |
Domain | IPR001791 | Laminin G domain |
Domain | IPR002049 | Laminin-type EGF domain |
Domain | IPR008211 | Laminin, N-terminal |
Domain | IPR009254 | Laminin alpha, domain I |
Domain | IPR010307 | Laminin domain II |
Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
Domain Details Per Protein
Protein | Length | Concanavalin A-like lectin/glucanase domain superfamily | EGF-like domain | Laminin alpha, domain I | Laminin domain II | Laminin G domain | Laminin IV | Laminin, N-terminal | Laminin-type EGF domain |
---|---|---|---|---|---|---|---|---|---|
UniProtKB:D7PSA0
|
3664 | ||||||||
UniProtKB:F1QKW3
|
3664 | ||||||||
UniProtKB:Q2Q1W5
|
3664 | ||||||||
UniProtKB:Q5BLH6
|
526 |
Interactions and Pathways
No data available
Plasmids
No data available