ZFIN ID: ZDB-GENE-030131-9790
Gene Name: ATP-binding cassette, sub-family A (ABC1), member 12
Gene Symbol: abca12

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Previous Names: cb352 (1), sb:cb352

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Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 7 figures from 2 publications
Directly Submitted Expression Data: 6 figures (12 images) from Thisse et al., 2001 [cb352]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth)
  epidermis, EVL, mucus secreting cell, olfactory placode (all 8) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la026982Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa2502 Point Mutation Unknown Premature Stop ENU
    sa9840 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18961 Point Mutation Unknown Premature Stop ENU
    sa34715 Point Mutation Unknown Premature Stop ENU
    sa41498 Point Mutation Unknown Splice Site ENU
    Targeting reagents: MO1-abca12 (1)
    PHENOTYPE
    Data: 2 figures from Li et al., 2011
    Observed in: ball, epidermis, epidermis morphogenesis, keratinocyte cell surface (all 6) expand
    DISEASE ASSOCIATED WITH abca12 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    autosomal recessive congenital ichthyosis 4A Ichthyosis, congenital, autosomal recessive 4A 601277
    autosomal recessive congenital ichthyosis 4B Ichthyosis, autosomal recessive 4B (harlequin) 242500
    Ontology GO Term
    Biological Process epidermis morphogenesis (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003439 (1)
  • InterPro:IPR003593 (1)
  • InterPro:IPR017871 (1)
  • InterPro:IPR026082 (1)
  • InterPro:IPR027417 (1)
  • InterPro:IPR030371 (1)
  • PROSITE:PS00211 (1)
  • PROSITE:PS50893 (1)
  • Pfam:PF00005 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA abca12-001 (1) 6192
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM abca12 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    abca12Contained in: [BAC] CH211-207D8 (1) (order this), DKEY-124M15 (1) (order this)
    abca12Encodes: [EST] cb352 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_681540 (1) 18813bp
    Genomic GenBank:CR753890 (1) 201771bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1Q7A5 (1) 2592aa
    Sequence Clusters UniGene:155623 (1)
    Sequence Information (all 19)
    OTHER abca12 GENE PAGES
  • Gene:558335 (1)
  • VEGA:OTTDARG00000025947 (1)
  • Ensembl(GRCz10):ENSDARG00000074749 (1)
  • ORTHOLOGY for abca12 (Chr: 9)
    CITATIONS (20)