Gene

akap12b

ID
ZDB-GENE-030131-9753
Name
A kinase (PRKA) anchor protein 12b
Symbol
akap12b Nomenclature History
Previous Names
  • akap12
  • cb27 (1)
  • fb72g12
  • gravin (1)
  • id:ibd1202
  • sb:cb27
  • si:ch73-192g21.1
  • wu:fb72g12
  • wu:fc21c03
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have protein kinase A binding activity. Involved in several processes, including bleb assembly; negative regulation of Rho protein signal transduction; and slow muscle cell migration. Localizes to perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in chronic kidney disease; colorectal carcinoma; and juvenile myelomonocytic leukemia. Is expressed in several structures, including cardiovascular system; germ ring; mesoderm; nervous system; and tail bud. Orthologous to human AKAP12 (A-kinase anchoring protein 12).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
13 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With akap12b Human Ortholog
No data available
Associated With akap12b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001573 A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif
Family IPR028540 A-kinase anchor protein 12
Domain Details Per Protein
Protein Length A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif A-kinase anchor protein 12
UniProtKB:A0A0R4IC31 1596
UniProtKB:A5HLY6 1533
UniProtKB:A0A2R8QBS2 1506
UniProtKB:A0A2R8Q9F2 1596
UniProtKB:F2Z4T4 1533
UniProtKB:A0A0A0MPJ0 216
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations