ZFIN ID: ZDB-GENE-030131-9753
Gene Name: A kinase (PRKA) anchor protein 12b
Gene Symbol: akap12b
Sequence Ontology ID : SO:0000704

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Previous Names: akap12, cb27 (1), fb72g12, gravin (1), id:ibd1202, sb:cb27, si:ch73-192g21.1, wu:fb72g12, wu:fc21c03

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(Including Attributions)
Location: Chr: 20 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 12 figures from 4 publications
Directly Submitted Expression Data: 5 figures (7 images) from Thisse et al., 2001 [cb27]
  4 figures (5 images) from Kudoh et al., 2001 [ibd1202]
Wild-type Stages, Structures: Blastula:Sphere (4.0h-4.33h) to Pharyngula:Prim-25 (36.0h-42.0h)
  adaxial cell, artery, blood vasculature, brain (all 24) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb67 Indel Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • ihb68 Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • ihb69 Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • la010281Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa72 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15047 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43450 Point Mutation Unknown Premature Stop ENU
    sa43451 Point Mutation Unknown Premature Stop ENU
    Targeting reagents: CRISPR1-akap12b (1), MO1-akap12b (1), MO2-akap12b (1), MO3-akap12b (1), MO4-akap12b (1) (all 6) expand
    PHENOTYPE
    Data: 7 figures from 3 publications
    Observed in: bleb assembly, convergent extension, convergent extension involved in axis elongation, heart looping (all 17) expand
    DISEASE ASSOCIATED WITH akap12b HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell morphogenesis (more)
    Cellular Component cytoplasm (more)
    Molecular Function protein kinase A binding (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001573
  • InterPro:IPR028540
  • Pfam:PF03832
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA akap12b-001 (1) 6450
    akap12b-002 (1) 648
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM akap12b No data available
    MARKER RELATIONSHIPS
    akap12bContained in: [BAC] CH73-109I14 (1) (order this), CH73-192G21 (1) (order this), DKEY-147L14 (1) (order this)
    akap12bContains: [SNP] rs3729026 (1)
    [STS] chunp30253
    akap12bEncodes: [EST] cb27 (1) (order this), fb72g12 (1), fc21c03, ibd1202 (order this), wz11325, wz12504 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001281788 (1) 6521bp
    Genomic GenBank:CR926887 184926bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IC31 1596aa
    Sequence Clusters UniGene:104704 (1)
    Sequence Information (all 29)
    OTHER akap12b GENE PAGES
  • Alliance (1)
  • Gene:567365 (1)
  • VEGA:OTTDARG00000024841 (1)
  • Ensembl(GRCz10):ENSDARG00000055678 (1)
  • ORTHOLOGY for akap12b (Chr: 20)
    CITATIONS (29)