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ZIRC
ZFIN ID: ZDB-GENE-030131-9662
Gene Name: RAP1B, member of RAS oncogene family
Gene Symbol: rap1b    Nomenclature History

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Previous Names: cb1026 (1), cb119 (1), sb:cb119 (1), wu:fb11c04 (1), wu:fb74e09 (1), wu:fk70e05 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Exhibits MAP kinase kinase activity. Involved in chordate embryonic development; convergent extension; and heart development. Localizes to the cell-cell junction. Is expressed in several structures, including brain; cardiovascular system; floor plate; hindbrain neural plate; and hypochord. Orthologous to human RAP1B (RAP1B, member of RAS oncogene family).
Genome Resources: Alliance (1),  Gene:321107 (1),  Ensembl(GRCz11):ENSDARG00000008867 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la015359Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • ncv124 Small Deletion Unknown Unknown TALEN
    ncv125 Indel Unknown Unknown TALEN
    sa20258 Point Mutation Unknown Missense, Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31395 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-rap1b
    2
    MO1-rap1b N/A 4
    MO2-rap1b N/A 3
    MO3-rap1b N/A 2
    MO4-rap1b N/A 3
    TALEN1-rap1b 1
    DISEASE ASSOCIATED WITH rap1b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH rap1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cartilage morphogenesis (more)
    Cellular Component cell-cell junction (more)
    Molecular Function MAP kinase kinase activity (more)
    GO Terms (all 23)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA rap1b-202 (1)    Ensembl 2885
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rap1b
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    tg(fli1a:egfp-rap1b) fli1a EGFPrap1b Danio rerio 1 1
    MARKER RELATIONSHIPS
    rap1b Contained in: [BAC] DKEY-31F5 (1) (order this)
    rap1b Encodes: [EST] cb119 (1) (order this), cb1026 (1) (order this), fb11c04, fb74e09, fk70e05
    [cDNA] MGC:55940 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_199533 (1) 2284 bp
    Genomic GenBank:BX649534 (1) 205347 bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q6TEN1 (1) 184 aa
    Sequence Clusters UniGene:76648 (1)
    Sequence Information (all 21)
    ORTHOLOGY for rap1b ( Chr: 4 )
    CITATIONS (37)