Gene

gsna

ID
ZDB-GENE-030131-9653
Name
gelsolin a
Symbol
gsna Nomenclature History
Previous Names
  • gsn
  • cb107 (1)
  • sb:cb107
  • u-gelsolin (1)
  • wu:fi16f06
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have actin filament binding activity and calcium ion binding activity. Predicted to be involved in actin filament severing; actin nucleation; and barbed-end actin filament capping. Human ortholog(s) of this gene implicated in Finnish type amyloidosis. Is expressed in several structures, including cardiovascular system; digestive system; nervous system; neural tube; and trigeminal placode. Orthologous to human GSN (gelsolin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
21 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gsna Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Finnish type amyloidosis Alliance Amyloidosis, Finnish type 105120
Associated With gsna Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR007123 Gelsolin-like domain
Family IPR007122 Villin/Gelsolin
Homologous_superfamily IPR029006 ADF-H/Gelsolin-like domain superfamily
Domain Details Per Protein
Protein Length ADF-H/Gelsolin-like domain superfamily Gelsolin-like domain Villin/Gelsolin
UniProtKB:F1QUM3 729
UniProtKB:A0A8M9P366 738
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA gsna-201 (1) Havana 2918 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations