ZFIN ID: ZDB-GENE-030131-9653
Gene Name: gelsolin a
Gene Symbol: gsna    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: gsn, cb107 (1), sb:cb107, u-gelsolin (1), wu:fi16f06

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have actin filament binding activity and phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in several processes, including actin filament severing; actin polymerization or depolymerization; and barbed-end actin filament capping. Predicted to localize to actin cytoskeleton; cytoplasm; and extracellular space. Is expressed in several structures, including cardiovascular system; digestive system; nervous system; neural tube; and trigeminal placode. Human ortholog(s) of this gene implicated in Finnish type amyloidosis. Orthologous to human GSN (gelsolin).
Genome Resources: Alliance (1),  Gene:321099 (1),  Ensembl(GRCz11):ENSDARG00000011459 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa37268 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH gsna HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Finnish type amyloidosis Alliance Amyloidosis, Finnish type 105120
    DISEASE ASSOCIATED WITH gsna VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process actin filament severing (more)
    Cellular Component actin cytoskeleton (more)
    Molecular Function actin filament binding (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA gsna-201 (1)    Ensembl 2918
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gsna No data available
    MARKER RELATIONSHIPS
    gsna Contained in: [BAC] DKEYP-46G10 (1)
    gsna Encodes: [EST] cb107 (1) (order this), fc65c12 (1) (order this), fi16f06 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001012312 (1) 2547 nt
    Genomic RefSeq:NW_018395347 (1) Blast at MegaBLAST
    Polypeptide UniProtKB:A0JMI5 (1) 758 aa
    Sequence Information (all 32)
    ORTHOLOGY for gsna ( Chr: 21 )
    CITATIONS (22)