ZFIN ID: ZDB-GENE-030131-9563
Gene Name: carboxylesterase 3
Gene Symbol: ces3    Nomenclature History

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Previous Names: si:dkey-38l12.3, wu:fb66e04, wu:fi21c04, wu:fj87b08

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have hydrolase activity. Localizes to the motile cilium. Is expressed in liver. Orthologous to human CES2 (carboxylesterase 2) and CES3 (carboxylesterase 3).
Genome Resources: Alliance (1),  Gene:560651 (1),  Ensembl(GRCz11):ENSDARG00000041595 (1)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Segmentation:26+ somites (22.0h-24.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa23271 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-ces3 N/A 1
    DISEASE ASSOCIATED WITH ces3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ces3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component motile cilium (more)
    Molecular Function hydrolase activity (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR002018 Carboxylesterase, type B
    Conserved_site IPR019819 Carboxylesterase type B, conserved site
    Active_site IPR019826 Carboxylesterase type B, active site
    Homologous_superfamily IPR029058 Alpha/Beta hydrolase fold
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ces3-201 (1)    Ensembl 1748
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ces3 No data available
    MARKER RELATIONSHIPS
    ces3 Contained in: [BAC] DKEY-38L12 (1) (order this), DKEY-102F14 (1) (order this)
    ces3 Encodes: [EST] fb66e04 (1), fi21c04 (1), fj87b08, IMAGE:7045374
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001044936 (1) 1737 bp
    Genomic GenBank:BX005041 190853 bp
    Select Tool
    Polypeptide UniProtKB:Q5BJI3 (1) 553 aa
    Sequence Information (all 18)
    ORTHOLOGY for ces3 ( Chr: 18 )
    CITATIONS (21)