ZFIN ID: ZDB-GENE-030131-955
Gene Name: eukaryotic translation initiation factor 2B, subunit 4 delta
Gene Symbol: eif2b4
Sequence Ontology ID : SO:0000704

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Previous Names: si:ch211-101l18.4, wu:fb54a09 (1), zgc:110790

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(Including Attributions)
Location: Chr: 20 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have translation initiation factor activity; predicted to be involved in translational initiation; orthologous to human EIF2B4 (eukaryotic translation initiation factor 2B subunit delta).
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:110790]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa17367 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH eif2b4 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    leukoencephalopathy with vanishing white matter Leukoencephalopathy with vanishing white matter 603896
    Ovarioleukodystrophy 603896
    DISEASE ASSOCIATED WITH eif2b4 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cellular metabolic process (more)
    Cellular Component cytoplasm (more)
    Molecular Function translation initiation factor activity (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000649 (1)
  • InterPro:IPR037171 (1)
  • Pfam:PF01008 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA eif2b4-001 (1) 2120
    ncRNA eif2b4-002 (1) 794
    mRNA eif2b4-003 (1) 578
    ncRNA eif2b4-004 (1) 639
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM eif2b4 No data available
    MARKER RELATIONSHIPS
    eif2b4Contained in: [BAC] CH211-101L18 (order this)
    eif2b4Contains: [SNP] rs3729021 (1), rs3729022 (1)
    eif2b4Encodes: [EST] fb54a09, wz1304
    [cDNA] MGC:110790 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001014361 (1) 2150bp
    Genomic GenBank:BX276101 (1) 167149bp
    Select Tool
    Polypeptide UniProtKB:A0A286Y8J6 (1) 554aa
    Sequence Clusters UniGene:43296 (1)
    Sequence Information (all 22)
    OTHER eif2b4 GENE PAGES
  • Alliance (1)
  • Gene:541548 (1)
  • VEGA:OTTDARG00000004774 (1)
  • Ensembl(GRCz11):ENSDARG00000014004 (2)
  • ORTHOLOGY for eif2b4 (Chr: 20)
    CITATIONS (22)