Gene
adkb
- ID
- ZDB-GENE-030131-948
- Name
- adenosine kinase b
- Symbol
- adkb Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have adenosine kinase activity. Predicted to be involved in AMP salvage; phosphorylation; and purine ribonucleoside salvage. Predicted to localize to cytosol and nucleus. Is expressed in several structures, including alar plate midbrain region; liver; midbrain; musculature system; and segmental plate. Human ortholog(s) of this gene implicated in hypermethioninemia due to adenosine kinase deficiency. Orthologous to human ADK (adenosine kinase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2001
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb980 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Hypermethioninemia due to adenosine kinase deficiency | 614300 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Adenosine kinase | Carbohydrate kinase PfkB | Carbohydrate/purine kinase, PfkB, conserved site | Ribokinase-like |
---|---|---|---|---|---|
UniProtKB:Q7ZTT5
|
345 |
Interactions and Pathways
No data available
Plasmids
No data available