ZFIN ID: ZDB-GENE-030131-9322
Gene Name: arachidonate 5-lipoxygenase-activating protein
Gene Symbol: alox5ap
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: Flap (1), wu:fj65d02, zgc:63982

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 10 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have glutathione peroxidase activity, glutathione transferase activity, and leukotriene-C4 synthase activity; involved in angiogenesis; predicted to localize to the endoplasmic reticulum  ...
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa41707 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: Fig. S4b from KalĂ©n et al., 2009
    Observed in:
    DISEASE ASSOCIATED WITH alox5ap HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    cerebral infarction {Stroke, susceptibility to} 601367
    DISEASE ASSOCIATED WITH alox5ap VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process angiogenesis (more)
    Cellular Component integral component of membrane (more)
    Molecular Function enzyme activator activity (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001129 (1)
  • InterPro:IPR001446 (1)
  • InterPro:IPR023352 (1)
  • Pfam:PF01124 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA alox5ap-201 (1) 1304
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM alox5ap No data available
    MARKER RELATIONSHIPS
    alox5apContained in: [BAC] CH211-135J7 (1) (order this)
    alox5apEncodes: [EST] fj65d02
    [cDNA] MGC:63982 (1) (order this), MGC:192084 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200061 (1) 1327bp
    Genomic GenBank:BX548163 (1) 132400bp
    Select Tool
    Polypeptide UniProtKB:F1QKS8 (1) 156aa
    Sequence Clusters UniGene:48970 (1)
    Sequence Information (all 16)
    OTHER alox5ap GENE PAGES
  • Alliance (1)
  • Gene:337376 (1)
  • VEGA:OTTDARG00000022261 (1)
  • ORTHOLOGY for alox5ap (Chr: 10)
    CITATIONS (21)