ZFIN ID: ZDB-GENE-030131-9008
Gene Name: protein kinase, DNA-activated, catalytic polypeptide
Gene Symbol: prkdc
Sequence Ontology ID : SO:0000704

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Previous Names: fa96e12, wu:fa96e12 (1)

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(Including Attributions)
Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7147291]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fb103 Small Deletion Unknown Frameshift, Premature Stop TALEN
sa903 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa978 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa7082 Point Mutation Unknown Splice Site ENU
    sa12418 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa13311 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13548 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa16262 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa17162 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa21045 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21046 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa27016 Point Mutation Unknown Premature Stop ENU
    sa34147 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa34148 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40976 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40977 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • yu27 Indel Exon 3 Frameshift TALEN
    Targeting reagents:
    PHENOTYPE
    Data: 7 figures from Jung et al., 2016
    Observed in:
    DISEASE ASSOCIATED WITH prkdc HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Immunodeficiency 26, with or without neurologic abnormalities 615966
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process B cell differentiation (more)
    Cellular Component nucleus (more)
    Molecular Function ATP binding (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000403 (1)
  • InterPro:IPR003151 (1)
  • InterPro:IPR003152 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR012582 (1)
  • InterPro:IPR014009 (1)
  • InterPro:IPR016024 (1)
  • InterPro:IPR018936 (1)
  • InterPro:IPR036940 (1)
  • InterPro:IPR037706 (1)
  • PROSITE:PS00915 (1)
  • PROSITE:PS00916 (1)
  • PROSITE:PS50290 (1)
  • PROSITE:PS51189 (1)
  • PROSITE:PS51190 (1)
  • Pfam:PF00454 (1)
  • Pfam:PF02259 (1)
  • Pfam:PF02260 (1)
  • Pfam:PF08163 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA prkdc-001 (1) 12981
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM prkdc No data available
    MARKER RELATIONSHIPS
    prkdcContained in: [BAC] CH211-198H5 (1) (order this), DKEY-86L18 (1) (order this)
    prkdcEncodes: [EST] fa96e12, IMAGE:7147291 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_009303401 (1)
    Genomic GenBank:CT574559 (1) 110868bp
    Select Tool
    Polypeptide UniProtKB:E7F4J7 (1) 4119aa
    Sequence Clusters UniGene:159456 (1)
    Sequence Information (all 14)
    OTHER prkdc GENE PAGES
  • Alliance (1)
  • Gene:562283 (1)
  • VEGA:OTTDARG00000043953 (1)
  • Ensembl(GRCz10):ENSDARG00000075083 (1)
  • ORTHOLOGY for prkdc (Chr: 7)
    CITATIONS (23)