ZFIN ID: ZDB-GENE-030131-9008
Gene Name: protein kinase, DNA-activated, catalytic polypeptide
Gene Symbol: prkdc
Previous Names: fa96e12, wu:fa96e12 (1)
Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7147291]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
  unspecified
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
fb103 Unknown TALEN
sa903 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa978 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12418 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa13311 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13548 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16262 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17162 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21045 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21046 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH prkdc HUMAN ORTHOLOG 
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Immunodeficiency 26, with or without neurologic abnormalities 615966
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process double-strand break repair via nonhomologous end joining (more)
    Cellular Component nucleus (more)
    Molecular Function ATP binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000403 (1)
  • InterPro:IPR003151 (1)
  • InterPro:IPR003152 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR012582 (1)
  • InterPro:IPR014009 (1)
  • InterPro:IPR016024 (1)
  • InterPro:IPR018936 (1)
  • PROSITE:PS00915 (1)
  • PROSITE:PS00916 (1)
  • PROSITE:PS50290 (1)
  • PROSITE:PS51189 (1)
  • PROSITE:PS51190 (1)
  • Pfam:PF00454 (1)
  • Pfam:PF02259 (1)
  • Pfam:PF02260 (1)
  • Pfam:PF08163 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM prkdc No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    prkdcEncodes: [EST] fa96e12, IMAGE:7147291 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_009303401 (1) 12748bp
    Polypeptide UniProtKB:E7F4J7 (1) 4119aa
    Sequence Clusters UniGene:159456 (1)
    Sequence Information (all 11)
    OTHER prkdc GENE PAGES 
  • Gene:562283 (1)
  • Ensembl(GRCz10):ENSDARG00000075083 (1)
  • ORTHOLOGY for prkdc (Chr: 7) 
    Species Symbol Chromosome Accession # Evidence
    Human PRKDC 8
  • Gene:5591
  • OMIM:600899
  • HGNC:9413
  • Amino acid sequence comparison (1)
    Mouse Prkdc 16
  • MGI:104779
  • Gene:19090
  • Amino acid sequence comparison (1)
    Download Curated Orthology
    CITATIONS (13)