Gene
scarf1
- ID
- ZDB-GENE-030131-8778
- Name
- scavenger receptor class F, member 1
- Symbol
- scarf1 Nomenclature History
- Previous Names
-
- wu:fb07b12
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable low-density lipoprotein particle binding activity and scavenger receptor activity. Predicted to be involved in dendrite development; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; and neuron remodeling. Predicted to be active in membrane. Is expressed in lateral mesoderm. Orthologous to human SCARF1 (scavenger receptor class F member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Sumanas et al., 2005
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa10051 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa13509 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa14395 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa42563 | Allele with one point mutation | Unknown | Splice Site | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | EGF-like domain | Laminin-type EGF domain | MEGF10/SREC1/2-like |
|---|---|---|---|---|---|
| UniProtKB:E7FBT2 | InterPro | 888 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
scarf1-201
(1)
|
Ensembl | 5,082 nt | ||
| mRNA |
scarf1-202
(1)
|
Ensembl | 3,705 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-209M4 | ZFIN Curated Data | |
| Encodes | EST | fb07b12 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_001344339 (1) | 4159 nt | ||
| Genomic | GenBank:CR522882 (1) | 129430 nt | ||
| Polypeptide | UniProtKB:E7FBT2 (1) | 888 aa |
- Chestnut, B., Sumanas, S. (2019) Zebrafish etv2 knock-in line labels vascular endothelial and blood progenitor cells. Developmental Dynamics : an official publication of the American Association of Anatomists. 249(2):245-261
- Fink, I.R., Benard, E.L., Hermsen, T., Meijer, A.H., Forlenza, M., Wiegertjes, G.F. (2015) Molecular and functional characterization of the scavenger receptor CD36 in zebrafish and common carp. Molecular immunology. 63(2):381-93
- Gomez, G., Lee, J.H., Veldman, M.B., Lu, J., Xiao, X., and Lin, S. (2012) Identification of Vascular and Hematopoietic Genes Downstream of etsrp by Deep Sequencing in Zebrafish. PLoS One. 7(3):e31658
- Sumanas, S., Jorniak, T., and Lin, S. (2005) Identification of novel vascular endothelial-specific genes by the microarray analysis of the zebrafish cloche mutants. Blood. 106(2):534-541
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