ZFIN ID: ZDB-GENE-030131-8720
Gene Name: pentraxin 3, long a
Gene Symbol: ptx3a    Nomenclature History

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Previous Names: fb05a06, sb:eu1077, si:ch211-272f3.3, wu:fb05a06

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have complement component C1q binding activity. Predicted to be involved in innate immune response. Predicted to localize to the extracellular space. Is expressed in several structures, including epidermis; fin; hypochord; nervous system; and pectoral fin bud. Orthologous to human PTX3 (pentraxin 3).
Genome Resources: Alliance (1),  Gene:101887125 (1),  Ensembl(GRCz11):ENSDARG00000068275 (2)
GENE EXPRESSION
All Expression Data: 8 figures from 2 publications
Directly Submitted Expression Data: 7 figures (21 images) from Thisse et al., 2005 [eu1077]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa17589 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ptx3a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ptx3a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process innate immune response (more)
    Cellular Component extracellular space (more)
    Molecular Function complement component C1q complex binding (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR001759 Pentraxin-related
    Homologous_superfamily IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
    Conserved_site IPR030476 Pentaxin, conserved site
    Family IPR042837 Pentraxin-related protein PTX3
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ptx3a-201 (1)    Ensembl 2164
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ptx3a No data available
    MARKER RELATIONSHIPS
    ptx3a Contained in: [BAC] CH211-232P17 (1), CH211-272F3 (1)
    ptx3a Encodes: [EST] eu1077 (1), fb05a06, fb04g11 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005159231 (1)
    Genomic GenBank:BX255879 173755 bp
    Select Tool
    Polypeptide UniProtKB:A3KPN4 (1) 447 aa
    Sequence Information (all 18)
    ORTHOLOGY for ptx3a ( Chr: 18 )
    CITATIONS (21)