ZFIN ID: ZDB-GENE-030131-8191
Gene Name: protein kinase C, epsilon a
Gene Symbol: prkcea    Nomenclature History

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Previous Names: prkce, fj59b07, wu:fj59b07

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and peptidyl-serine phosphorylation. Is expressed in brain; peripheral neurons; and spinal cord. Orthologous to human PRKCE (protein kinase C epsilon).
Genome Resources: Alliance (1),  Gene:100005075 (1),  Ensembl(GRCz11):ENSDARG00000003008 (2)
GENE EXPRESSION
All Expression Data: 2 figures from Patten et al., 2007
Wild-type Stages, Structures: Hatching:Long-pec (48.0h-60.0h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la012164Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la018160Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH prkcea HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH prkcea VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process intracellular signal transduction (more)
    Molecular Function ATP binding (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA prkcea-201 (1)    Ensembl 4572
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-prkce polyclonal IgG Rabbit IHC, WB Santa Cruz Biotechnology, Inc.
    1
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM prkcea No data available
    MARKER RELATIONSHIPS
    prkcea Contained in: [BAC] DKEY-250C11 (1) (order this), DKEY-261G23 (1) (order this)
    prkcea Encodes: [EST] fj59b07
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_005156293 (1) 3350 nt
    Genomic GenBank:CR931998 (1) 144369 nt
    Select Tool
    Polypeptide UniProtKB:E7F368 (1) 744 aa
    Sequence Information (all 19)
    ORTHOLOGY for prkcea ( Chr: 12 )
    CITATIONS (23)