Gene

prkcea

ID
ZDB-GENE-030131-8191
Name
protein kinase C, epsilon a
Symbol
prkcea Nomenclature History
Previous Names
  • prkce
  • fj59b07
  • wu:fj59b07
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and peptidyl-serine phosphorylation. Predicted to localize to cytoplasm. Is expressed in brain; peripheral neurons; and spinal cord. Orthologous to human PRKCE (protein kinase C epsilon).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from Patten et al., 2007
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With prkcea Human Ortholog
No data available
Associated With prkcea Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000008 C2 domain
Domain IPR000719 Protein kinase domain
Domain IPR000961 AGC-kinase, C-terminal
Domain IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Domain IPR017892 Protein kinase, C-terminal
Domain IPR020454 Diacylglycerol/phorbol-ester binding
Domain IPR034669 Novel protein kinase C epsilon, catalytic domain
Family IPR014376 Protein kinase C, delta/epsilon/eta/theta types
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR035892 C2 domain superfamily
Domain Details Per Protein
Protein Length AGC-kinase, C-terminal C2 domain C2 domain superfamily Diacylglycerol/phorbol-ester binding Novel protein kinase C epsilon, catalytic domain Protein kinase, ATP binding site Protein kinase C, delta/epsilon/eta/theta types Protein kinase C-like, phorbol ester/diacylglycerol-binding domain Protein kinase, C-terminal Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:E7F368 744
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-prkce polyclonal IgG Rabbit
  • IHC
  • WB
Santa Cruz Biotechnology, Inc.
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations