ZFIN ID: ZDB-GENE-030131-8097
Gene Name: glutamate receptor, metabotropic 2a
Gene Symbol: grm2a    Nomenclature History

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Previous Names: mglur2a (1), wu:fj52c07

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have group II metabotropic glutamate receptor activity. Predicted to be involved in G protein-coupled glutamate receptor signaling pathway and regulation of glutamatergic synaptic transmission. Predicted to localize to integral component of plasma membrane. Is expressed in brain; retinal neural layer; and trigeminal ganglion. Orthologous to human GRM2 (glutamate metabotropic receptor 2).
Genome Resources: Alliance (1),  Ensembl(GRCz11):ENSDARG00000004150 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6072 Point Mutation Unknown Premature Stop ENU
sa10180 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20787 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33936 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH grm2a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH grm2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process G protein-coupled receptor signaling pathway (more)
    Cellular Component integral component of membrane (more)
    Molecular Function G protein-coupled receptor activity (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA grm2a-202 (1)    Ensembl 2560
    Browsers: EnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM grm2a No data available
    MARKER RELATIONSHIPS
    grm2a Contained in: [BAC] DKEYP-111E5 (1)
    grm2a Encodes: [EST] fj52c07
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA GenBank:AW280196 (1) 581 nt
    Genomic GenBank:BX664752 (1) 156503 nt
    Select Tool
    Polypeptide UniProtKB:E7FDL9 (1) 894 aa
    Sequence Information (all 6)
    ORTHOLOGY for grm2a ( Chr: 6 )
    CITATIONS (16)