ZFIN ID: ZDB-GENE-030131-8019
Gene Name: DnaJ (Hsp40) homolog, subfamily C, member 18
Gene Symbol: dnajc18    Nomenclature History

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Previous Names: fj47b06, wu:fj47b06 (1), zgc:172228

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have Hsp70 protein binding activity. Predicted to be involved in cellular response to misfolded protein; chaperone cofactor-dependent protein refolding; and ubiquitin-dependent ERAD pathway. Predicted to localize to the endoplasmic reticulum membrane. Orthologous to human DNAJC18 (DnaJ heat shock protein family (Hsp40) member C18).
Genome Resources: Alliance (1),  Gene:559928 (1),  Ensembl(GRCz11):ENSDARG00000056005 (2)
GENE EXPRESSION
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa9193 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37341 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dnajc18 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dnajc18 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cellular response to misfolded protein (more)
    Cellular Component endoplasmic reticulum membrane (more)
    Molecular Function Hsp70 protein binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR001623 DnaJ domain
    Domain IPR015399 Domain of unknown function DUF1977, DnaJ-like
    Conserved_site IPR018253 DnaJ domain, conserved site
    Homologous_superfamily IPR036869 Chaperone J-domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dnajc18-201 (1)    Ensembl 2696
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dnajc18 No data available
    MARKER RELATIONSHIPS
    dnajc18 Contained in: [BAC] CH211-59D17 (1)
    dnajc18 Encodes: [EST] fj47b06
    [cDNA] MGC:172228 (1), MGC:198159 (1), MGC:198161 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001113588 (1)
    Genomic GenBank:BX510945 (1) 202152 bp Blast at MegaBLAST
    Polypeptide UniProtKB:A8WG70 (1) 407 aa
    Sequence Clusters UniGene:6471 (1)
    Sequence Information (all 17)
    ORTHOLOGY for dnajc18 ( Chr: 21 )
    CITATIONS (18)