ZFIN ID: ZDB-GENE-030131-8005
Gene Name: succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
Gene Symbol: sdhb
Previous Names: fj46d06, wu:fj46d06
Location: Chr: 22 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 7 figures from 2 publications
Directly Submitted Expression Data: 5 figures (9 images) from Thisse et al., 2004 [IMAGE:6896418]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Adult (90d-730d, breeding adult)
  alar plate midbrain region, eye, immature eye, male organism (all 9) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH sdhb HUMAN ORTHOLOG 
Disease Ontology Term OMIM Term OMIM Phenotype ID
Cowden disease Cowden syndrome 2 612359
gastrointestinal stromal tumor Gastrointestinal stromal tumor 606764
paraganglioma Paragangliomas 4 115310
phaeochromocytoma Pheochromocytoma 171300
Paraganglioma and gastric stromal sarcoma 606864
GENE ONTOLOGY 
Ontology GO Term
Biological Process oxidation-reduction process (more)
Cellular Component mitochondrial inner membrane (more)
Molecular Function 2 iron, 2 sulfur cluster binding (more)
GO Terms (all 16)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001041 (1)
  • InterPro:IPR004489 (1)
  • InterPro:IPR006058 (1)
  • InterPro:IPR009051 (1)
  • InterPro:IPR012675 (1)
  • InterPro:IPR017896 (1)
  • InterPro:IPR017900 (1)
  • InterPro:IPR025192 (1)
  • PROSITE:PS00197 (1)
  • PROSITE:PS00198 (1)
  • PROSITE:PS51085 (1)
  • PROSITE:PS51379 (1)
  • Pfam:PF13085 (1)
  • EC:1.3.5.1 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    ANTIBODIES 
    AB1-sdhb (1)
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM sdhb No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    sdhbEncodes: [EST] fj46d06, IMAGE:6896418 (1) (order this)
    [cDNA] MGC:165456 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001098740 (1) 1199bp
    Genomic GenBank:CABZ01072696 (1) 6545bp
    Polypeptide UniProtKB:A5PL98 (1) 280aa
    Sequence Clusters UniGene:75182 (1)
    Sequence Information (all 13)
    OTHER sdhb GENE PAGES 
  • Gene:562149 (1)
  • Ensembl(GRCz10):ENSDARG00000075768 (1)
  • ORTHOLOGY for sdhb (Chr: 22) 
    Species Symbol Chromosome Accession # Evidence
    Human SDHB 1
  • Gene:6390
  • OMIM:185470
  • HGNC:10681
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (19)