Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030131-8005
Gene Name: succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
Gene Symbol: sdhb
Previous Names: fj46d06, wu:fj46d06
Location: Chr: 22   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 7 figures from 2 publications
Directly Submitted Expression Data: 5 figures (9 images) from Thisse et al., 2004 [IMAGE:6896418]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Hatching:Long-pec (48.0h-60.0h)
  alar plate midbrain region, eye, immature eye, myotome (all 8) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS No data available
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Cowden syndrome 2 612359
Gastrointestinal stromal tumor 606764
Paraganglioma and gastric stromal sarcoma 606864
Paragangliomas 4 115310
Pheochromocytoma 171300
GENE ONTOLOGY
Ontology GO Term
Biological Process oxidation-reduction process (more)
Cellular Component mitochondrial inner membrane (more)
Molecular Function 2 iron, 2 sulfur cluster binding (more)
GO Terms (all 16)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001041 (1)
  • InterPro:IPR004489 (1)
  • InterPro:IPR006058 (1)
  • InterPro:IPR009051 (1)
  • InterPro:IPR012675 (1)
  • InterPro:IPR017896 (1)
  • InterPro:IPR017900 (1)
  • InterPro:IPR025192 (1)
  • PROSITE:PS00197 (1)
  • PROSITE:PS00198 (1)
  • PROSITE:PS51085 (1)
  • PROSITE:PS51379 (1)
  • Pfam:PF13085 (1)
  • EC:1.3.5.1 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    ANTIBODIES
    AB1-sdhb (1)
    CONSTRUCTS WITH SEQUENCES FROM sdhb No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    sdhb Encodes: [EST] fj46d06, IMAGE:6896418 (1) (order this)
    [cDNA] MGC:165456 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001098740 (1) 1199 bp
    Genomic GenBank:CABZ01072696 (1) 6545 bp
    Polypeptide UniProtKB:A5PL98 (1) 280 aa
    Sequence Clusters UniGene:75182 (1)
    Sequence Information (all 13)
    OTHER sdhb GENE PAGES
  • Gene:562149 (1)
  • Ensembl(Zv9):ENSDARG00000075768 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish sdhb 22  
    Human SDHB 1 (1p36.1-p35)
  • OMIM:185470
  • Gene:6390
  • Orthology Details
    CITATIONS (19)