ZFIN ID: ZDB-GENE-030131-8005
Gene Name: succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
Gene Symbol: sdhb
Previous Names: fj46d06, wu:fj46d06
Location: Chr: 22   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 7 figures from 2 publications
Directly Submitted Expression Data: 5 figures (9 images) from Thisse et al., 2004 [IMAGE:6896418]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Adult (90d-730d, breeding adult)
  alar plate midbrain region, eye, immature eye, male organism (all 9) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH sdhb HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Cowden disease Cowden syndrome 2 612359
gastrointestinal stromal tumor Gastrointestinal stromal tumor 606764
phaeochromocytoma Pheochromocytoma 171300
Paraganglioma and gastric stromal sarcoma 606864
Paragangliomas 4 115310
GENE ONTOLOGY
Ontology GO Term
Biological Process oxidation-reduction process (more)
Cellular Component mitochondrial inner membrane (more)
Molecular Function 2 iron, 2 sulfur cluster binding (more)
GO Terms (all 16)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001041 (1)
  • InterPro:IPR004489 (1)
  • InterPro:IPR006058 (1)
  • InterPro:IPR009051 (1)
  • InterPro:IPR012675 (1)
  • InterPro:IPR017896 (1)
  • InterPro:IPR017900 (1)
  • InterPro:IPR025192 (1)
  • PROSITE:PS00197 (1)
  • PROSITE:PS00198 (1)
  • PROSITE:PS51085 (1)
  • PROSITE:PS51379 (1)
  • Pfam:PF13085 (1)
  • EC:1.3.5.1 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    ANTIBODIES
    AB1-sdhb (1)
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM sdhb No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    sdhb Encodes: [EST] fj46d06, IMAGE:6896418 (1) (order this)
    [cDNA] MGC:165456 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001098740 (1) 1199 bp
    Genomic GenBank:CABZ01072696 (1) 6545 bp
    Polypeptide UniProtKB:A5PL98 (1) 280 aa
    Sequence Clusters UniGene:75182 (1)
    Sequence Information (all 13)
    OTHER sdhb GENE PAGES
  • Gene:562149 (1)
  • Ensembl(Zv9):ENSDARG00000075768 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish sdhb 22  
    Human SDHB 1 (1p36.1-p35)
  • OMIM:185470
  • Gene:6390
  • Orthology Details
    CITATIONS (19)